Tonifying speen and tonifying kidney granular and its prepn. method

A technology for strengthening the spleen and nourishing the kidney and granules, which can be used in pharmaceutical formulations, medical preparations containing active ingredients, and bulk delivery, etc. To achieve the effect of enhancing immunity, improving drug efficacy, and improving long-term survival rate

Inactive Publication Date: 2006-09-20
重庆希尔安药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] ② Gastrointestinal adverse reactions: Radiotherapy and chemotherapy can cause damage to the gastrointestinal mucosa. In mild cases, stomach discomfort, nausea and vomiting, and loss of appetite; Electrolyte and acid-base balance disorders, severe malnutrition, etc., thereby reducing the patient's quality of life
[0008] As mentioned above, the adverse reactions caused by radiotherapy and chemotherapy not only affect the quality of life of patients, but also make many cancer patients unable to bear their pain and give up treatment, leading to treatment failure and ultimately shortening the survival period of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0136] API:

[0137] Codonopsis 9g, Lycium barbarum 16g, Ligustrum lucidum 15g, Atractylodes macrocephala 8g, Cuscuta 6g, Psoralen 2.9g;

[0138] Preparation method: Soak the raw materials Codonopsis pilosula, Lycium barbarum, Ligustrum lucidum, Atractylodes macrocephala, Cuscuta, and psoralen in water with 8 times the weight of the raw materials for 30 minutes, and then decoct for 1.5 hours to obtain a decoction; add 6 times the weight of raw materials for the second time Decoct the weight of the drug in water for 0.5 hour, combine the decoction, let it stand for 24 hours, filter, and concentrate the filtrate to a clear paste with a relative density of 1.10. The temperature for measuring the relative density is 50°C. The auxiliary material is used as the base material and spray-dried to prepare the granule. In the spray drying, the inlet air temperature is 75°C, the material temperature is 60°C, and the drying time is 1 hour

Embodiment 2

[0140] API:

[0141] Codonopsis 11g, Lycium barbarum 14.9g, Ligustrum lucidum 18g, Atractylodes macrocephala 8.9g, Cuscuta 4.9g, Psoralen 0.5g;

[0142] Preparation method: Soak the raw materials Codonopsis pilosula, Lycium barbarum, Ligustrum lucidum, Atractylodes macrocephala, Cuscuta, and psoralen in water with 7 times the weight of the raw materials for 40 minutes, then decoct for 1.2 hours to obtain a decoction; add 5 times the raw materials for the second time Decoct the weight of the drug in water for 1.5 hours, combine the decoction, let it stand for 18 hours, filter, and concentrate the filtrate to a clear paste with a relative density of 1.30. The temperature for measuring the relative density is 50°C. The auxiliary material is used as the base material and spray-dried to prepare the granule. In the spray drying, the inlet air temperature is 70°C, the material temperature is 65°C, and the drying time is 1.5 hours

Embodiment 3

[0144] API:

[0145] Codonopsis 14.9g, medlar 7g, privet privet 10g, Atractylodes macrocephala 10g, dodder 1g, psoralen 6g;

[0146] Preparation method: Soak the raw materials Codonopsis pilosula, Lycium barbarum, Ligustrum lucidum, Atractylodes macrocephala, Cuscuta, and psoralen in water with 6 times the weight of the raw materials for 20 minutes, and then decoct for 2 hours to obtain a decoction; add 4 times the raw materials for the second time Decoct the weight of medicine in water for 2 hours, combine the decoction, let it stand for 12 hours, filter, and concentrate the filtrate to a clear paste with a relative density of 1.25. The temperature for measuring the relative density is 50°C. The auxiliary material is used as the base material and spray-dried to prepare the granule. In the spray drying, the inlet air temperature is 90°C, the material temperature is 70°C, and the drying time is 0.5 hours

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PUM

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Abstract

A Chinese medicine in the form of particles for treating the toxic by-effect after chemicotherapy of cancer patient, and invigorating the function of spleen and kidney is prepared from 6 Chinese-medicinal materials including pilose asiabell root, wolfberry fruit, white atractylodes rhizome, lucid ligustrum fruit, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to Jianpi Yishen granules for treating tumor patients with side effects caused by radiotherapy and chemotherapy, and spleen and kidney deficiency and a preparation method thereof. Background technique [0002] Radiotherapy and chemotherapy are destructive treatments, which can greatly damage the normal tissues and organs of the body and destroy the immune function of the body. Cancer patients undergoing radiotherapy and chemotherapy can cause various side effects. [0003] ①Bone marrow suppression: The damage to the blood system caused by radiotherapy and chemotherapy is the most common clinical phenomenon. In mild cases, the number of peripheral blood cells decreases, but it can be recovered after stopping treatment; in severe cases, it leads to bone marrow suppression, which significantly reduces the peripheral blood cells of the patient. If the white blood cells are ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K9/16A61P1/14
Inventor 唐德江陈犁
Owner 重庆希尔安药业有限公司
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