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Method for preparing Rhizoma cimicifugae formula granules

A formula granule and quality technology, which is applied in the direction of medical formula, medical preparations containing active ingredients, bulk transportation, etc., can solve the problems that there are no public reports on the preparation process of Cimicifuga formula granules, and achieve convenient and easy administration. The effect of simple storage and process

Inactive Publication Date: 2006-10-25
TIANJIN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is no public report on the preparation process of Cimicifuga formula granules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0008] Take 20g Cimicifuga decoction pieces, add 160g water, reflux at 99°C for 1.5 hours, and reflux for extraction 3 times. Evaporate the extract in a water bath at 60° C. to obtain 7.4 g of dry extract, add 7.5 g of soluble starch as an auxiliary material, and add 5 ml of 75% ethanol to make a soft material. The soft material is passed through a No. 14 sieve to make granules, dried under normal pressure at 60°C, and double-sieved with No. 1 and No. 5 sieves to obtain Cimicifuga formula granules.

example 2

[0010] Take 20g Cimicifuga decoction pieces, add 200g water, reflux at 100°C for 2 hours, and reflux extraction 3 times. Evaporate the extract in a water bath at 60° C. to obtain 10.4 g of dry extract, add 10.4 g of soluble starch as an auxiliary material, and add 9 ml of 75% ethanol to make a soft material. The soft material is passed through a No. 14 sieve to make granules, dried under normal pressure at 60°C, and double-sieved with No. 1 and No. 5 sieves to obtain Cimicifuga formula granules.

example 3

[0012] Take 20g Cimicifuga decoction pieces, add 240g water, reflux at 100°C for 1.5 hours, and reflux extraction 3 times. The extract was dried in a water bath at 60° C. to obtain 11.4 g of dry extract, 11.4 g of soluble starch was added as an auxiliary material, and 9.5 ml of 95% ethanol was added to make a soft material. The soft material is passed through a No. 14 sieve to make granules, dried under normal pressure at 60°C, and double-sieved with No. 1 and No. 5 sieves to obtain Cimicifuga formula granules.

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PUM

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Abstract

The present invention discloses a preparation method of cimicifuga root prescription granules. Said method includes the following steps: adding water into cimicifuga root decocting pieces, making counter-current extraction with reflux at 98-100 deg.C, drying extract at 50-80 deg.C in water bath to obtain dried extract, adding auxiliary material including soluble starch, cane sugar powder, dextrin or lactose and adding ethyl alcohol to make them into soft material, sieving, granulating and drying so as to obtain the invented cimicifuga root prescription granules.

Description

technical field [0001] The invention relates to a method for preparing Cimicifuga formula granules, which belongs to the preparation technology of traditional Chinese medicine formula granules. Background technique [0002] Cimicifuga is one of the most commonly used traditional Chinese medicines. It has the functions of expelling rash, clearing away heat and detoxification, and enhancing Yang Qi. For wind-heat headache, toothache, aphthous sores, sore throat, impermeable measles, spots of impotence, prolapse of the anus, prolapse of the uterus, etc. Cimicifuga is widely used clinically, with remarkable curative effect and safe medication. Existing Cimicifugae preparations include traditional decoctions (decoction pieces), extracts (infusions), tablets, granules, etc. Compared with Cimicifuga formula granules, it has the advantages of being easy to carry and store, and suitable for formulating prescriptions according to the theory of traditional Chinese medicine. [0003]...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K9/16A61K125/00A61P1/02A61P11/04A61P15/00A61P43/00
Inventor 高文远刘新桥邓轶渊陈海霞
Owner TIANJIN UNIV