Traditional Chinese medicine soft capsule for treating rheumatism and ostalgia, and its prepn. method
A technology for rheumatoid bone pain and soft capsule, which can be used in capsule delivery, pharmaceutical formulations, non-central analgesics, etc., can solve problems such as aggravating bone damage in rheumatoid arthritis, and achieve fast onset, no harmful residue, and easy control. Effect
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Embodiment 1
[0026] Take 30g of Zhichuanwu, 30g of Zhicaowu, 30g of safflower, 30g of licorice, 30g of papaya, 30g of black plum, 30g of ephedra, and grind them into fine powder, sieve, and mix well; The other four flavors such as safflower are decocted twice with water, each time for 2 hours, the decoction is combined, filtered, the filtrate is concentrated to a thick paste, the above-mentioned fine powder is added, mixed, dried, crushed into a fine powder of the main drug, and set aside .
[0027] Take by weighing 100g of the above-mentioned principal agent fine powder, add 897g of soybean oil containing 4% beeswax, 1.9g of dibutyl hydroxytoluene, 0.2g of benzyl p-hydroxyformate, and 1.9 of opacifier, and grind for 2 minutes through a colloid mill to prepare Obtain the contents of the soft capsule. Weigh glycerin, water, and gelatin in proportion (1:2:2), mix glycerin and water evenly, put them into a plastic tank, add gelatin when heated to 65°C, stir and heat to 70°C, keep warm for 40...
Embodiment 2
[0029] The preparation method of the main drug fine powder is the same as that of the previous example.
[0030] Take by weighing 600g of the above-mentioned principal ingredient fine powder, add 397g of soybean oil containing 4% beeswax, 1.9g of dibutyl hydroxytoluene, 0.2g of benzyl p-hydroxyformate, 1.9 of opacifier, and grind for 2 minutes through a colloid mill to prepare Obtain the contents of the soft capsule. Weigh glycerin, water, and gelatin according to the ratio (1-3:3-6:2.8-5.5), mix glycerin and water evenly, put them into a plastic tank, add gelatin when heated to 60°C, stir and heat to 65°C , keep warm for 40 minutes, vacuumize (-0.02~-0.06MPa), stir for about 1 hour, until there are no air bubbles in the tank, pass through a 60-mesh filter and place it in a heat preservation tank, keep it warm at about 60°C, and prepare a rubber solution for later use . Start the soft capsule machine, and after the rubber runs to meet the requirements, use liquid paraffin to...
Embodiment 3
[0032] The preparation method of the main drug fine powder is the same as that of the previous example.
[0033]Take by weighing 200g of the above-mentioned principal agent fine powder, add 797g of soybean oil containing 4% beeswax, 1.9g of dibutyl hydroxytoluene, 0.2g of benzyl p-hydroxyformate, 1.9 of opacifier, and grind for 2 minutes through a colloid mill to prepare Obtain the contents of the soft capsule. Weigh glycerin, water, and gelatin in proportion (1.5-2.5:3.5-5:3.5-4.5), mix glycerin and water evenly, put them into a plastic tank, add gelatin when heated to 65°C, stir and heat to 70°C , keep warm for 40 minutes, evacuate (-0.02~-0.06MPa), stir for about 1 hour, until there are no bubbles in the tank, pass through a 60-mesh filter and arrange in a heat preservation tank, keep warm at 60±5°C to prepare a rubber solution ,spare. Start the soft capsule machine, and after the rubber runs to meet the requirements, use liquid paraffin to adjust the weight of the pill. ...
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