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Blood platelet-increasing tablet, its preparation process and quality control method

A technology for raising platelets and Indigo Naturalis, applied in the field of new dosage forms of traditional Chinese medicine, can solve the problems of easy moisture absorption, low quality control indicators, difficult to control tablets with different loadings, etc., and achieves beautiful appearance, easy to control the difference in tablet weight, and easy to take. and the effect of carrying

Inactive Publication Date: 2006-12-20
ANHUI AN TECH MEDICAL & BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Shengxue Platelet Capsules is a collection of national Chinese patent medicine standards issued by the State Food and Drug Administration Bureau, and local standards of Chinese patent medicines have risen to national standards. The difference is more difficult to control than tablets; more importantly, the quality control index is low. The original process of licorice and other water extractions contains polysaccharides and other moisture-absorbing components, resulting in unstable quality during storage and easy to absorb moisture and deteriorate.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] (1) Prescription: Qingdai 167g, Forsythia 500g, Agrimony 500g

[0032]Moutan bark 833g Licorice 250g

[0033] Dextrin 40g Calcium Sulfate 40g Sodium Carboxymethyl Starch 20g

[0034] The above is made into 1000 pieces

[0035] (2) Preparation method:

[0036] The above five medicinal materials are ground into fine powder with Indigo Daisy; Agrimony and Cortex Moutan are extracted twice with 5 times the amount of 80% ethanol, each time for 2 hours, combined with the second ethanol extract, filtered, recovered ethanol and concentrated under reduced pressure to a relative A thick paste with a density of 1.25-1.30 (60°C); soak forsythia in water for 4 hours, extract the volatile oil by steam distillation for 6 hours, store the volatile oil in another container, and keep the decoction for future use. Add 6 times the amount of dregs and licorice to decoct and extract twice, decoct for 1.5 hours each time, combine the decoction for the second time with the...

Embodiment 2

[0055] (1) Prescription: Qingdai 167g, Forsythia 500g, Agrimony 500g

[0056] Moutan bark 833g Licorice 250g

[0057] Starch 80g Calcium Sulfate 50g Sodium Carboxymethyl Starch 18g

[0058] The above is made into 1000 pieces

[0059] (2) Preparation method:

[0060] The above five medicinal materials are ground into fine powder with Qingdai; Agrimony is extracted twice with 5 times the amount of 65% ethanol, each time for 2 hours, combined with the second ethanol extract, filtered, recovered ethanol and concentrated under reduced pressure to a relative density of 1.25 ~1.30 (60°C) thick ointment; soak forsythia and peony cortex in water for 4 hours, extract volatile oil by steam distillation for 6 hours, store the volatile oil in a separate container, and keep the water decoction for later use; add 6 times the amount of decoction of medicinal dregs and licorice to extract 2 times, decocting for 1.5 hours each time, the second decoction was combined with the above decoction,...

Embodiment 3

[0062] (1) Prescription: Qingdai 167g, Forsythia 500g, Agrimony 500g

[0063] Moutan bark 833g Licorice 250g

[0064] Starch 60g Calcium Sulfate 30g Microcrystalline Cellulose 30g Crospovidone 15g

[0065] The above is made into 1000 pieces

[0066] (2) Preparation method:

[0067] The above five medicinal materials are ground into fine powder with Qingdai; Agrimony and Glycyrrhizae are extracted twice with 5 times the amount of 60% ethanol, each time for 2 hours, combined with the second ethanol extract, filtered, recovered ethanol and concentrated under reduced pressure to a relative density 1.25~1.30(60℃) thick ointment; soak Moutan Cortex and Forsythia in water for 4 hours, extract volatile oil by steam distillation for 6 hours, store volatile oil in another container, keep water decoction for later use; add 6 times the amount of decoction to extract medicinal dregs 2 times, decocting for 1.5 hours each time, the second decoction was combined ...

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Abstract

The invention relates to a tablet for increasing platelet content, method for preparation and quality control, wherein the raw material herbs include natural indigo, capsule of weeping forsythia, hairy vein agrimony, bark of peony root and licorice root.

Description

technical field [0001] The invention relates to a new dosage form of traditional Chinese medicine, in particular to traditional Chinese medicine Shengxue Platelet Tablet and its preparation method and quality control technology. Background technique [0002] Shengxue Platelet Capsules is a collection of national Chinese patent medicine standards issued by the State Food and Drug Administration Bureau, and local standards of Chinese patent medicines have risen to national standards. The difference is more difficult to control than tablets; more importantly, the quality control index is low. The water extraction of the original process such as licorice contains polysaccharides and other moisture-absorbing components, resulting in unstable quality during storage and easy moisture absorption and deterioration. The present invention researches and develops the variety with a new formulation, a new preparation process, and a new quality standard, and selects a film-coated tablet t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/73A61K9/20A61P7/04G01N30/90G01N30/02G01N33/15
Inventor 余世春
Owner ANHUI AN TECH MEDICAL & BIOLOGICAL TECH
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