Dispersant tablets of honeysuckle flower and coptis

A technology of dispersible tablets and Yinhuang, which is applied in the direction of medical preparations containing active ingredients, plant/algae/fungus/moss components, plant raw materials, etc., can solve the problem that Yinhuang dispersible tablets have no disintegration time, and achieve room for maneuver Great effect of improving disintegration

Inactive Publication Date: 2007-04-04
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] There is no record of specific disintegration time in CN02128009.6, a kind of preparation method of Yinhuang dispersible tablet that has been reported

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Chinese medicine raw materials of Yinhuang Dispersible Tablets: 100 grams of honeysuckle extract, 40 grams of Scutellaria baicalensis extract.

[0056] The weight percentage of traditional Chinese medicine extract and auxiliary materials of Yinhuang dispersible tablet: 35% of fine powder of Yinhuang extract, 22% of low-substituted hydroxypropyl cellulose, 16% of sodium carboxymethyl starch, 4% of microcrystalline cellulose, lactose 18%, Polyvinylpyrrolidone 3%, Magnesium Stearate 2%.

[0057] Yinhuang dispersible tablets are obtained according to the following specific steps: take honeysuckle, add water to decoct twice, each time for 2 hours, combine the decoction, filter, add lime milk to the filtrate to adjust the pH value to 10-12, let it stand, and filter Precipitate, add appropriate amount of water, add sulfuric acid to adjust the pH value to 6-7, stir well, filter, concentrate the filtrate to a thick paste, and dry to obtain the honeysuckle extract. Take Scutella...

Embodiment 2

[0060] The fine powder of silvery yellow extract in percentage by weight 27%, sodium carboxymethylcellulose 22%, microcrystalline cellulose 11%, cross-linked polyvinylpyrrolidone 16%, polyvinylpyrrolidone 5%, lactose 12%, polyvinylpyrrolidone 4%, micronized silica gel 1%, magnesium lauryl sulfate 2%. All the other are with embodiment 1.

Embodiment 3

[0062] 38% by weight of fine powder of silver yellow extract, 20% sodium carboxymethyl starch, 15% croscarmellose sodium, 6% crospovidone, 3% low-substituted hydroxypropyl cellulose, Mannitol 7%, polyvinylpyrrolidone 7%, micronized silica gel 2%, magnesium stearate 1%, HLB=15-16 sucrose fatty acid ester 1%. Sucrose fatty acid ester is P-1570 or P-1670 or LWA-1570, all the other are the same as embodiment 1.

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PUM

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Abstract

An Yinhuang dispersing tablet for treating tonsillitis, pharyngolaryngitis and upper respiratory tract infection is prepared from honeysuckle flower, scutellaria root and proper additive.

Description

technical field [0001] The invention relates to the technical field of Chinese patent medicine dispersible tablets, in particular to a silver-yellow dispersible tablet. Background technique [0002] Dispersible tablets are a new drug dosage form developed in recent years. Yinhuang has many dosage forms, which have the functions of clearing away heat, detoxification and anti-inflammation. For acute and chronic tonsillitis, acute and chronic pharyngitis, upper respiratory tract infection. One of the original dosage forms, Yinhuang sugar-coated tablets, has been included in the Chinese Pharmacopoeia. The dissolution of Yinhuang sugar-coated tablets is slow, the absorption is poor, and the bioavailability is not high. [0003] Compared with ordinary tablets, dispersible tablets require that the temperature of the disintegration medium is 20±1°C, the disintegration time limit is less than 3 minutes, and all the disintegrated particles should pass through the No. 2 sieve. The d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/539A61K36/355A61K9/20A61P11/04
Inventor 罗晓健杨世林王跃生饶毅魏惠珍王金钱张爱玲
Owner JIANGXI HERBFINE HI TECH
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