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Application of psammophytes strawflower total saponin in preparing medicine

A technology of Helichrysum serrata and total saponins is applied to the application field of Helichrysum serratia total saponins in the preparation of medicines, can solve the problems of no relevant reports and the like, and achieves simple process, safe use, and obvious effects of lowering blood sugar and lipids. Effect

Inactive Publication Date: 2010-04-21
新疆维吾尔药业有限责任公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, through the retrieval of a large number of relevant documents, there is no relevant report on the effect of total saponins of Helichrysum saponifera on lowering blood sugar and blood lipids.

Method used

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  • Application of psammophytes strawflower total saponin in preparing medicine
  • Application of psammophytes strawflower total saponin in preparing medicine
  • Application of psammophytes strawflower total saponin in preparing medicine

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0088] Embodiment 1 (based on 1 kilogram)

[0089] Take 1 kg of the traditional Chinese medicine Helichrysum chrysanthemum, cut into 2mm conventional decoction pieces, first degrease with petroleum ether with a distillate of 30°C, and then extract three times with 30% ethanol of 3 times the amount;

[0090] The extract is decolorized with 2% medicinal activated carbon, filtered, and ethanol is recovered;

[0091] Dilute to 1500ml with deionized water again, filter, purify through D101 macroporous adsorption resin column, wherein preferably contain the water of 70% ethanol and 30 ℃ of ethanol eluents through macroporous adsorption resin, wash with deionized water earlier nearly to Colorless, then elute with 20% ethanol, collect the ethanol liquid, concentrate under reduced pressure to recover ethanol, concentrate and dry to obtain the total saponins of Helichrysum saponins, 1kg of total saponins of Helichrysum chrysanthemum, 0.5kg of medicinal starch, and use 80% ethanol Wet g...

Embodiment 2

[0092] Embodiment 2 (based on 1 kilogram)

[0093] Take 1 kg of the traditional Chinese medicine Helichrysum chrysanthemum, cut into 2 mm conventional decoction pieces, first degrease with petroleum ether with a distillate of 50 ° C, and then extract three times with 5 times the amount of 50% ethanol; the extract is decolorized with 2% medicinal activated carbon, filtered , recovery of ethanol;

[0094]Dilute to 1500ml with deionized water again, filter, purify through D101 macroporous adsorption resin column, wherein preferably contain the water of 70% ethanol and 30 ℃ of ethanol eluents through macroporous adsorption resin, wash with deionized water earlier nearly to Colorless, then elute with 50% ethanol, collect the ethanol solution, concentrate under reduced pressure to recover ethanol, concentrate and dry to obtain the total saponins of Helichrysum chrysanthemum, heat 1.5kg polyethylene glycol 4000 on a water bath for 1h to obtain a solution, and Add 0.5 kg of Helichrys...

Embodiment 3

[0095] Embodiment 3 (based on 1 kilogram)

[0096] Take 1 kg of the traditional Chinese medicine Helichrysum chrysanthemum, cut into 2mm conventional decoction pieces, first degrease with petroleum ether with a distillate of 45°C, and then extract three times with 6 times the amount of 60% ethanol;

[0097] The extract is decolorized with 2% medicinal activated carbon, filtered, and ethanol is recovered;

[0098] Then dilute to 1500ml with deionized water, filter, purify through D101 macroporous adsorption resin column, wash with 30°C deionized water until colorless, then elute with 60% ethanol, collect ethanol liquid, concentrate under reduced pressure to recover ethanol , concentrating and drying to obtain total saponins of Helichrysum, 1kg of total saponins of Helichrysum, 0.5kg of starch, 1kg of dextrin, appropriate amount of 50% ethanol, granulating, granulating, drying, tableting, 0.3g per tablet, other items It should meet the requirements of the tablet items in the Ph...

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Abstract

An application of the sabulose immortelle's saponin in preparing the hypoglycemic medicine in various possible forms for treating diabetes is disclosed.

Description

technical field [0001] The present invention relates to the application of total saponins of Helichrysum chrysanthemum as a drug for treating diabetes and lowering blood sugar, including the prevention and treatment of type I diabetes and type II diabetes, and can also be made into health food for the prevention of diabetes and auxiliary treatment of patients . Background technique [0002] Diabetes is a systemic chronic progressive disease. Its basic pathology is absolute or relative insufficient insulin secretion, endocrine disorders caused by decreased sensitivity of β cells to insulin, which in turn leads to metabolic disorders of sugar, protein, fat, water and electrolytes in the human body. With the prolongation of time, it is easy to be complicated with systemic vascular disease, which seriously threatens human health and life safety. [0003] At present, diabetes and its complications have become one of the main diseases that threaten human health. With the improve...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/28A61K9/00A61P3/10A61P3/06
Inventor 阿吉艾克拜尔·艾萨吕辉牟新利信学雷
Owner 新疆维吾尔药业有限责任公司