Orally administrable composition for the photoprotection of the skin

a composition and orally administrable technology, applied in the field of orally administrable compositions or pharmaceutical compositions, cosmetical compositions, etc., can solve the problems of inducing accelerated skin ageing, skin problems, and ultraviolet radiation affecting a variety of immune responses in living beings, so as to reduce the effects of solar radiation-related stress on skin, and improve skin protection and coloration

Inactive Publication Date: 2005-03-31
NESTEC SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0012] The combination according to the present invention has a particular beneficial effect on skin protection and coloration of the skin that helps to reduce the effects of solar radiation-related stress on skin.

Problems solved by technology

Although exposure to ultraviolet radiation is needed for humans to produce vitamin D, growing evidence suggests that extensive exposure to sun-light, in particular to ultraviolet radiation, causes a variety of problems in the skin, including induction of certain skin cancers and induction of accelerated skin ageing.
In addition to these established health concerns, research has also provided evidence suggesting that exposure to ultraviolet radiation may negatively affect a variety of immune responses in living beings both locally, within the UV-irradiated skin, and also systemically, i.e. at sites distant from the irradiated skin.
In J. Invest. Dermatol., 97 (1991), 624-628 it is reported that topical application of ultraviolet radiation-absorbing compounds (sunscreens) is effective in preventing ultraviolet radiation-induced erythema and edema but cannot prevent UV-light induced immuno-suppression.
This finding was confirmed by several other studies, according to which sunscreens seems to prevent inflammation or irritation but do not provide complete prophylactic protection against the immuno-suppressive effects of ultraviolet radiation.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0036] A photoprotective daily orally administrable composition is prepared as follows:

β-carotene4.7mgLatobacillus CNCM I-1225 dry mix50mgGlucidex IT 19 (maltodextrin powder)QSP 500mg

[0037] The composition is administered to the individual in an amount of 2×500 mg daily, which provides a protective and preventive effect of the skin.

example 2

[0038] A photoprotective daily orally administrable composition is prepared as follows:

β-carotene4.7mgZeaxanthine10mgLatobacillus CNCM I-1225 dry mix50mgGlucidex IT 19 (maltodextrin powder)QSP 500mg

[0039] The composition is administered to the individual in an amount of 2×500 mg daily, which provides a protective and preventive effect of the skin.

example 3

[0040] A photoprotective daily orally administrable composition is prepared as follows:

β-carotene4.7mgLycopene2.5mgBifidobacterium CNCM I-2168 dry mix30mgLatobacillus CNCM I-1225 dry mix30mgGlucidex IT 19 (maltodextrin powder)QSP 500mg

[0041] The composition is administered to the individual in an amount of 2×500 mg daily, which provides a protective and preventive effect of the skin.

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Abstract

An orally administrable composition for the photoprotection of the skin which comprises the combination of i) at least one probiotic lactic acid bacterium or a culture supernatant thereof, and ii) at least one carotenoid or derivative, included into an orally acceptable carrier.

Description

FIELD OF THE INVENTION [0001] The present invention relates to orally administrable composition or pharmaceutical compositions, or cosmetical compositions, for the protection of the skin against negative effects from the environment, in particular exposure to solar radiation, which is orally administrable, and a method to improve the photoprotection of the skin. BACKGROUND OF THE INVENTION [0002] The continuous decrease of the atmosphere's ozone layer with the concurrent increase of ultraviolet radiation reaching the planet's surface has attracted a great deal of interest in its potential consequence on human health. Although exposure to ultraviolet radiation is needed for humans to produce vitamin D, growing evidence suggests that extensive exposure to sun-light, in particular to ultraviolet radiation, causes a variety of problems in the skin, including induction of certain skin cancers and induction of accelerated skin ageing. [0003] In addition to these established health concern...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K8/31A61K31/015A61K31/07A23L1/30A61P17/16A61Q17/04C12N1/20
CPCA61K35/745A61Q17/04A61K8/99A61K2800/92A61K35/747A61K36/062A61K8/31A61K31/07A61K31/015A61K2300/00A61P17/16A61K35/74A61K8/67
Inventor BRETON, LIONELBUREAU-FRANZ, ISABELLEFANCHON, CHANTAL
Owner NESTEC SA
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