Methods for detecting, diagnosing and treating human renal cell carcinoma

a human renal cell carcinoma and gene expression technology, applied in the field of cancer research, can solve the problems incurable renal cell carcinoma, and largely ineffective existing systemic therapies in affecting disease response or patient survival, so as to improve the survival rate of renal cell carcinoma, cure, or stabilize the disease, and prevent or treat renal cell carcinoma.
US20050130193A1Inactive Publication Date: 2005-06-16LUXON BRUCE A +2

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
LUXON BRUCE A
Publication Date
2005-06-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

Gene expression profiling and hierarchical clustering analysis readily identify differential gene expressions in normal renal epithelial cells and renal cell carcinomas. Genes identified by this analysis would be useful for diagnosis, prognosis and development of targeted therapy for the prevention and treatment of conventional renal cell carcinoma.
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Description

CROSS-REFERENCE TO RELATED APPLICATION

[0001] This non-provisional patent application claims benefit of provisional patent application 60 / 502,038, filed Sep. 10, 2003, and 60 / 539,838, filed Jan. 28, 2004, now abandoned.BACKGROUND OF THE INVENTION

[0002] 1. Field of the Invention

[0003] The present invention relates generally to the field of cancer research. More specifically, the present invention relates to gene expression profiling for human renal cell carcinoma.

[0004] 2. Description of the Related Art

[0005] Renal cell carcinoma (RCC) represents a major health issue. The American Cancer Society predicts 31,900 new cases will be diagnosed in the United States alone in the year 2003, with 11,900 people dying of the disease. When clinically localized or even locally advanced, renal cell carcinoma can be surgically resected for cure using a variety of approaches. With metastatic progression, however, renal cell carcinoma is incurable, and existing systemic therapies are largely inef...

Claims

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