Non-neurotoxic plasminogen activating factors for treating of stroke
Patent Information
- Authority / Receiving Office
- US · United States
- Current Assignee / Owner
- PAION GMBH
- Publication Date
- 2006-06-29
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
RELATED APPLICATION
[0001] This is a continuation of application Ser. No. 10 / 184,01 filed Jun. 28, 2002, which claims the benefit of priority to German Patent Application No. 101 53 601.1, filed on Nov. 2, 2001, and European Patent Application No. 01 130 006.8 filed on Dec. 17, 2001, all of which are incorporated herein by reference.FIELD OF THE INVENTION
[0002] The invention pertains to the therapeutic use of non-neurotoxic plasminogen activators especially from the saliva of Desmodus rotundus (DSPA) preferentially for the treatment of stroke. BACKGROUND OF THE INVENTION
[0003] The term “stroke” is a general term that covers conditions having different clinical symptoms. For example, a stroke may be caused by an ischaemic or haemorrhagic insult.
[0004] Ischaemic insults (ischaemia) are characterized in a reduction or interruption of the blood circulation in the brain due to a lack of arterial blood supply. Often this is caused by thrombosis of an arteriosclerotic stenosed vessel or...