The invention relates to application of 2-bromopalmitic acid
nose drops in preparation of
antidepressant drugs, and belongs to the technical field of biological medicines. The invention discloses an application of 2-bromopalmitic acid
nose drops in preparation of
antidepressant drugs, and 2-bromopalmitic acid is used for blocking an AMPA (2-bromo-2-methylpropanoic acid) type
glutamate receptor lower membrane and promoting the stability of the AMPA type
glutamate receptor membrane. The pharmaceutical composition has a quick-acting anti-depression effect in a mouse
depression model, and is good in safety and free of
addiction.