Controlled release pharmaceutical compositions comprising a fumaric acid ester

a technology of controlled release and pharmaceutical compositions, which is applied in the direction of drug compositions, immunological disorders, metabolism disorders, etc., can solve the problems that fumarate therapy like e.g. fumaderm® often gives rise to gastrointestinal side effects, and achieve the effect of reducing gastrointestinal side effects and reducing gi (gastro-intestinal) side effects
US20090304790A1Inactive Publication Date: 2009-12-10BIOGEN SWISS MFG GMBH
81 Cites 107 Cited by

Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
BIOGEN SWISS MFG GMBH
Publication Date
2009-12-10
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The present invention relates to controlled release pharmaceutical compositions comprising fumaric acid ester(s) as active substance(s). The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designated to release the fumaric acid ester in a controlled manner so that local high concentrations of the active substance within the gastrointestinal tract upon oral administration can be avoided and, thereby, enabling a reduction in gastro-intestinal related side-effects.
Need to check novelty before this filing date? Find Prior Art

Description

CROSS-REFERENCE TO PRIOR APPLICATIONS

[0001] This is a U.S. National Phase Application under 35 U.S.C. §371 of International Patent Application No. PCT / DK2005 / 000648 filed Oct. 7, 2005, and claims the benefit of Danish Patent Applications: PA 2004 01546 filed Oct. 8, 2004; PA 2004 01736 filed Nov. 10, 2004; PA 2005 00211 filed Feb. 11, 2005; PA 2005 00419 filed Mar. 23, 2005; and U.S. Provisional Application No. 60 / 691,513 filed Jun. 16, 2005, all of which are hereby incorporated by reference in their entireties. The International Application was published in English on Apr. 13, 2006 as WO 2006 / 037342 A3 under PCT Article 21(2).FIELD OF THE INVENTION

[0002] The present invention relates to controlled release pharmaceutical compositions comprising a fumaric acid ester as an active substance. The compositions are suitable for use in the treatment of e.g. psoriasis or other hyperproliferative, inflammatory or autoimmune disorders and are designed to release the fumaric acid ester in a cont...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More