Methods and solutions for killing or deactivating spores

a technology of spores and methods, applied in the field of methods and solutions for killing or deactivating spores, can solve the problems of difficult to kill or deactivate anthrax spores, anthrax is a frequently fatal disease, and anthrax spores are among the most difficult to kill or deactivate spores

Active Publication Date: 2015-09-24
GOJO IND INC
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Anthrax is a disease that is frequently fatal due to the ability of this bacterium to produce deadly toxins.
B. anthracis also forms spores Inhalation of anthrax spores is frequently fatal, particularly if treatment is not started prior to the development of symptoms.
Anthrax spores are also among the most

Method used

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  • Methods and solutions for killing or deactivating spores
  • Methods and solutions for killing or deactivating spores
  • Methods and solutions for killing or deactivating spores

Examples

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Embodiment Construction

[0020]Plasmas, or ionized gases, have one or more free electrons that are not bound to an atom or molecule. Plasmas may be generated using a variety of gases including, air, nitrogen, noble gases (He, Ar, Xe, Kr, etc), oxygen, carbon dioxide and mixtures thereof under an electric field. In addition, non-thermal plasmas provide high concentrations of energetic and chemically active species. They can operate far from thermodynamic equilibrium with high concentrations of active species and yet remain at a temperature that is substantially the same as room temperature. The energy from the free electrons may be transferred to additional plasma components creating additional ionization, excitation and / or dissociation. Fluid that is contacted with plasma becomes “activated” and is referred to herein as plasma activated fluid, and in some embodiments, the plasma activated fluid is plasma activated water.

[0021]In some embodiments, plasmas may contain superoxide anions [O2·−], which react wit...

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Abstract

Exemplary methods and systems for killing or deactivating spores include applying a fluid to a surface containing a spore; and applying direct or indirect plasma to the surface for a period of time. In some embodiments, the fluid includes water. In some embodiments, the spore is Clostridium difficile and in some is Bacillus Anthracis. In some embodiments, the fluid is in the form of a mist and in some is in the form of a vapor. In some embodiments, peroxynitrite is created in the fluid during the method. Another exemplary embodiment of killing or deactivating a spore includes treating spores with direct plasma or an indirect plasma for a period of time and applying an antimicrobial to the spores. In some embodiments, the antimicrobial is an alcohol, a bleach or an alcohol-based sanitizer.

Description

TECHNICAL FIELD[0001]The present invention relates generally to methods and solutions for fast killing or deactivating spores.BACKGROUND OF THE INVENTION[0002]Spore formation is a sophisticated mechanism by which some Gram positive bacteria survive conditions of external stress and nutrient deprivation by producing a multi-layered protective capsule enclosing their dehydrated and condensed genomic DNA. When such bacterial spores encounter a favorable environment, germination can take place enabling the bacteria to reproduce, and, in the case of pathogenic species, cause disease. Bacterial spores possess a coat and membrane structure that is highly impermeable to most molecules that could be toxic to the dormant bacteria. Therefore, spores are highly resistant to damage by heat, radiation, and many of the commonly employed anti-bacterial agents, and generally can only be destroyed by some severe chemical procedures including oxidizing vapors such as hydrogen peroxide, chlorine dioxid...

Claims

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Application Information

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IPC IPC(8): A61L2/14A61L2/18A01N59/00A01N61/00A01N31/00
CPCA61L2/14A01N61/00A61L2/18A01N59/00A01N31/00A61L2/0011A61L2/0088A61L2/186A01N31/02
Inventor TSAI, TSUNG-CHANKALGHATGI, SAMEERPAPPAS ANTONAKAS, DAPHNEGRAY, ROBERT L.
Owner GOJO IND INC
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