Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

A sensor composition for acetone detection in breath

Active Publication Date: 2015-10-22
COUNCIL OF SCI & IND RES
View PDF0 Cites 12 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The present invention aims to provide an improved composition for detecting low concentrations of acetone in breath, as well as a process for preparing the same. Additionally, the invention is about developing a metal oxide semiconductor-based composition that can selectively detect acetone in the presence of high levels of moisture in breath.

Problems solved by technology

However, an early detection of diabetes can lower the potential dangers of the killer disease.
However, the process is expensive, and on the top, an invasive one.
So far, no non-invasive household gadget is available in the market for monitoring diabetes.
The drawbacks of the so far studied metal oxide semiconductor sensors are:i) The sensitivity for detecting the acetone concentration in the low ppm or sub-ppm range is not high enough for making devices.ii) The prior art reported sensors are moisture sensitive and hence are not selective to acetone in presence of high moisture (normally present in breath).

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A sensor composition for acetone detection in breath
  • A sensor composition for acetone detection in breath
  • A sensor composition for acetone detection in breath

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0050]In order to prepare a composition having 5.7 wt % Sb2O3, 1.4 wt % Pt and 92.9 wt % γ-Fe2O3, the following solutions were prepared: a) 2.424 g Fe(NO3)3.9H2O (Merck, 99% purity) in 250 mL distilled water, b) 6.25 g NH2NH2.H2O (Hydrazine) (Qualigens, 99% purity) in 250 mL of distilled water, c) 0.0124 g anhydrous PtCl4 (Merck) in 20 mL distilled water in presence of 2 mL concentrated HCl with continuous stirring for 1 h at 100° C. and d) 0.0046 g SbCl3 (Sigma-Aldrich, 99% purity) in 20 mL of distilled water in presence of 3 mL concentrated HCl with continuous stirring for 1 h at 100° C.

[0051]The aqueous solutions of the iron salt, antimony salt, platinum salt were mixed together in a 500 mL beaker and the final volume of the solution was adjusted to 300 mL followed by stirring for 10 min. The solution in the beaker was placed under a sonicator (ultrasonic processor, Sonics, 1500 Watt, model VCF1500) and the probe (diameter ˜2 cm) dipping length in the solution was ˜4 cm. During t...

example 2

[0054]In order to prepare a composition having 2.9 wt % Sb2O3, 1.4 wt % Pt and 95.7 wt % γ-Fe2O3, the following solutions were prepared: a) 2.424 g Fe(NO3)3.9H2O (Merck, 99% purity) in 250 mL distilled water, b, 6.25 g NH2NH2H2O (Qualigens, 99% purity) in 250 mL of distilled water, c) 0.0124 g anhydrous PtCl4 (Merck) in 20 mL distilled water in presence of 2 mL concentrated HCl with continuous stirring for 1 h at 100° C. and d) 0.0023 g SbCl3 (Sigma-Aldrich, 99% purity) in 20 mL of distilled water in presence of 3 mL concentrated HCl with continuous stirring for 1 h at 100° C.,

[0055]The aqueous solutions of the iron salt, antimony salt, platinum salt were mixed together in a 500 mL beaker and the final volume of the solution was adjusted to 300 mL followed by stirring for 10 min. The solution in the beaker was placed under a sonicator (ultrasonic processor, Sonics, 1500 Watt, model VCF1500) and the probe (diameter ˜2 cm) dipping length in the solution was ˜4 cm. During the sonicatio...

example 3

[0057]In order to prepare a composition having 9.9 wt % Sb2O3, 2.6 wt % Pt and 87.5 wt % γ-Fe2O3, the following solutions were prepared: a) 2.424 g Fe(NO3)3.9H2O (Merck, 99% purity) in 250 mL distilled water, b) 6.25 g NH2NH2.H2O (Qualigens, 99% purity) in 250 mL of distilled water, c) 0.0248 g anhydrous PtCl4. (Merck) in 20 mL distilled water in presence of 2 mL concentrated HCl with continuous stirring for 1 h at 100° C. and d) 0.0085 g SbCl3 (Sigma-Aldrich, 99% purity) in 2.0 mL of distilled water in presence of 3 mL concentrated HCl with continuous stirring for 1 h at 100° C.

[0058]The aqueous solutions of the iron salt, antimony salt, platinum salt were mixed together in a 500 mL beaker and final volume of the solution was adjusted to 300 mL followed by stirring for 10 min. The solution in the beaker was placed under a sonicator (ultrasonic processor, Sonics, 1500 Watt, model VCF1500) and the probe (diameter ˜2) dipping length in the solution was ˜4 cm, During the sonication (so...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention provides a composition for acetone detection and a process of preparation thereof. The composition comprises γ-ferric oxide (γ-Fe2O3), antimony (Sb) salt, and platinum (Pt). The sensor fabricated using the said composition is selective to low concentration of breath acetone, the biomarker of diabetes, in presence of high amount of moisture normally present in breath. Such semiconductor sensors for diabetes monitoring are inexpensive, rugged, patient-friendly and on the top, non-invasive.

Description

FIELD OF THE INVENTION[0001]The present invention relates to the field of diagnostic methods and composition. More particularly, it relates to a composition for acetone detection. More specifically, it relates to a composition for acetone detection in breath useful for diabetic diagnostics and a process of preparation thereof. The composition of the present invention comprises γ-ferric oxide (γ-Fe2O3), antimony (Sb) salt, and platinum (Pt).BACKGROUND OF THE INVENTION[0002]The menace of diabetes is all pervading across the globe and with the growing rate of diabetic patients. India is going to be the capital of diabetes soon. However, an early detection of diabetes can lower the potential dangers of the killer disease. Blood sugar monitoring (Fasting plasma glucose and Oral glucose tolerance test) is a time-tested reliable method of diabetes detection. However, the process is expensive, and on the top, an invasive one. To get around the problem, different non-invasive and minimally-i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N33/497B01J19/10
CPCG01N33/497G01N2033/4975B01J19/10A61B5/082A61B5/083G01N33/64A61B5/14532G01N33/4975
Inventor SEN, AMARNATHRANA, SUBHASIS
Owner COUNCIL OF SCI & IND RES
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com