The present invention relates to a Lactuca sativa seed designated 79-69 RZ, which exhibits a combination of traits including resistance to downy mildew races B1:1 to B1:28, CA-I, CA-IIA, CA-IIB, CA-III to CA-VIII (Bremia lactucae) and currant-lettuce aphid (Nasonovia ribisnigri) biotype Nr:0, and which has crisp, deeply red, deeply dentate leaves, and exhibits very slow bolting. The present invention also relates to a Lactuca sativa plant produced by growing the 79-69 RZ seed. The invention further relates to methods for producing the lettuce cultivar, represented by lettuce variety 79-69 RZ.