The invention provides a mobile phone protection shell capable of assisting the increasing of a playing volume of a mobile phone, and the mobile phone protection shell comprises a bottom wall, a side wall and a sound system, wherein the sound system comprises an earphone plug, an earphone wire, a volume adjuster and a sound box, the bottom wall and the side wall collectively encircle to form a cavity for accommodating the mobile phone, the surface of the bottom wall in the cavity is a front surface, a part on the side wall, corresponding to an earphone jack on the mobile phone, is provided with an earphone plug through hole, the back surface of the bottom wall which is close to the earphone plug through hole is provided with a projection, an earphone plug accommodating hole is arranged in the projection, the back surface of the bottom wall is also provided with a plurality of protruded patterns, and the sound box is embedded in the protruded patterns. When the play volume is loud, the earphone plug is plugged into the earphone jack on the mobile phone through the earphone plug through hole, and the sound box embedded in the protruded patterns can play a role in increasing the volume, so that the mobile phone protection shell not only can realize a decoration and protection function, but also can play a role in increasing the play volume.