Tech. of preparing 2-amino-4-acetamido methyl-phenoxide

Abstract

A process for preparing 2-amino-4-acetamino phenylmether includes such steps as catalytic hydroreducing reaction between methanol, 2,4-dinitro phenylmether and catalyst, solid-liquid separation, recovering catalyst, adding acid binding agent and the methanol solution of acetic anhydride, acelating reaction, cooling while crystallizing, filtering to obtain filtered cake recrystallizing in methanol, and separation.

Description

technical field

[0001] The invention relates to a process for preparing 2-amino-4-acetamidoanisole, which belongs to the technical field of fine chemicals. Background technique

[0002] 2-Amino-4-acetylaminoanisole, its English name is 4-Acetamino-2-aminoanisol, its molecular formula is C 9 h 12 N 2 o 2 Its molecular weight is 180.21, and its chemical molecular structure formula is:

[0003]

[0004] 2-Amino-4-acetamidoanisole is a white solid crystal with a melting point of 116°C to 118°C. It is an important intermediate for the production of dark varieties of disperse dyes (blue). Disperse dyes are the largest of the seven categories of dyes, with an annual output of 300,000 tons of finished products worldwide, while dark varieties account for 70% of the first class of dyes, and 90% of the coupling components in disperse dyes use aniline, 2-amino-4- Acetaminoanisole and m-acetamidoaniline are raw materials, wherein 2-amino-4-acetamidoanisole accounts for more than ...

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