Biological-degradable chitosan porous hemostasis material and its preparing method
A technology of biodegradable and hemostatic materials, applied in the field of chitosan porous hemostatic materials and its preparation, can solve the problems of adverse effects on the human body and non-degradable materials, and achieve the effects of enhanced hemostatic effect, large specific surface area, and enhanced water absorption performance
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[0027] 1. Preparation of Chitosan Porous Microspheres
[0028] 2g of chitosan with a degree of deacetylation of 90% and a viscosity average molecular weight of 500,000 was dissolved in 98g of 3% acetic acid aqueous solution, 5g of Tween 80 was added, and then 20g of vegetable soybean oil was added, stirred vigorously, and emulsified uniformly. Add the above emulsion dropwise to 1000ml of vigorously stirred n-hexane containing 60g Span 85, emulsify for 1 hour, add 2ml of 20% glutaraldehyde aqueous solution, continue to stir for 1 hour, filter and wash off soybean oil with 50% ethanol aqueous solution And emulsifier, and then freeze-dried to obtain porous chitosan microspheres.
[0029] 2. Preparation of Chitosan Porous Fiber
[0030] 3g of chitosan with a degree of deacetylation of 90% and a viscosity average molecular weight of 500,000 was dissolved in 97g of 5% acetic acid aqueous solution, 5g Triton x-100 and 10ml of n-hexane were added, stirred vigorously, and emulsified. The e...
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