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Method for preparing extractive of liuyueqing and its application

A water extract and preparation technology, applied in the field of preparation and application of Chinese herbal medicine, can solve problems that have not yet been discovered

Inactive Publication Date: 2007-10-03
黄仁彬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, no report has been found that the active parts of Liu Yueqing water extract and alcohol extract have been made into medicinal preparations and applied clinically.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] 3. The preparation method of the petroleum ether part of the lily lily is as follows: the coarse powder of lily lily is soaked in 80% ethanol with 10 times the concentration, soaked for 30 minutes, refluxed for 2 hours, and filtered. Add 8 times the amount of 80% ethanol to the dregs, extract by reflux for 1 hour, and filter. The two filtrates were combined and centrifuged (3000γ / min) for 15 min. After recovery of ethanol, the extract was collected, concentrated under reduced pressure, extracted 4 times with petroleum ether, chlorophyll was removed, and the ether phase was collected, and the ether phase was recovered to obtain the part of lilac petroleum ether.

[0022] 4. The preparation method of the 60% ethanol part of Liuyueqing is as follows: the coarse powder of Liuyueqing is added with 10 times the concentration of 80% ethanol, soaked for 30 minutes, refluxed for 2 hours, and filtered. Add 8 times the amount of 80% ethanol to the dregs, extract by reflux for 1 h...

Embodiment

[0052] 1. Extraction of Liuqing water extract and preparation of its preparation:

[0053] 1.1 Preparation of Liuyueqing water extract: Take 10kg of dried lily powder, add 100L of water, boil 3 times, 2h each time, filter, collect the boiled liquid, and concentrate it into a thick paste with a specific gravity of 1.3.

[0054] 1.2 Preparation of water extract tablets: take 10kg of dry lichen powder, prepare a thick paste with the same method as item 1.1, weigh and record the weight of the thick paste, add 2 times the amount of edible starch, and add 80% alcohol to mix, pass Sieve and granulate, dry at 60°C, granulate, add 3% talcum powder, 4% sodium carboxymethyl starch, compress into tablets (0.3g / tablet for plain tablets), and coat sugar-coated tablets (or film-coated tablets) , after the visual inspection conforms to the regulations.

[0055] 1.3 Preparation of water extract capsules: take 10kg of dried lichen powder, prepare a thick paste with the same method as item 1.1,...

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PUM

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Abstract

An extract composed of the aquatic extract, alcohol extract, petroether extract and ethanol extract is prepared from the Chinese-medicinal material 'Liuyueqing' through breaking, extracting and separating. It can be used to prepare the medicines for protecting liver and treating hepatitis B, hepatic injury, and cancer.

Description

technical field [0001] The invention relates to the preparation and application of a kind of Chinese herbal medicine, in particular to the preparation and medical application of water extract, ethanol extract, petroleum ether part and 60% ethanol part of Junipernia officinalis. Background technique [0002] Liuyueqing (LYQ) is the dry above-ground part of Taraphochlamys affinis (Griff) Bremekhu (Strobilanthes affinis (griff) Y.C.Tang) of the plant Acanthaceae (Acanthaceae). The contriver has carried out a large amount of researches to this medicine, and experiment finds, this product is to carbon tetrachloride (CCl 4 ) in rats caused by acute chemical liver injury has a protective effect, can reduce the activity of alanine aminotransferase (ALT) and aspartate aminotransferase (AST), increase the weight of thymus in immunosuppressed mice, improve serum lysozyme, The content of tumor necrosis factor (TNF-α); can increase the content of tumor necrosis factor (TNF-α) and interl...

Claims

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Application Information

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IPC IPC(8): A61K36/195A61K9/20A61K9/48A61K9/16A61K9/08A61K9/10A61P1/16A61P35/00A61P37/02
Inventor 黄仁彬蒋伟哲张士军林兴莫国艳林军刘曦荣延平曾嵘黄权芳梁霜
Owner 黄仁彬
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