Compounds and their use for treating somatic mutation-related diseases

A compound and hydrate technology, applied in the field of inhibiting premature translation termination associated with nonsense mutations in mRNA, treating or preventing diseases related to nonsense mutations in mRNA, can solve the problem of developing clitocine analogs or derivatives without reports , did not disclose clitocine and other issues
CN101076337AInactive Publication Date: 2007-11-21PTC THERAPEUTICS INC
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
PTC THERAPEUTICS INC
Publication Date
2007-11-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to methods, compounds, and compositions for treating or preventing diseases associated with nonsense mutations in an mRNA by administering the compounds or compositions of the present invention. More particularly, the present invention relates to methods, compounds, and compositions for suppressing premature translation termination associated with a nonsense mutation in an mRNA.
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Description

[0001] related application

[0002] Pursuant to 35 U.S.C. §119, this application claims U.S. Application 60 / 617,634, filed October 13, 2004, U.S. Application 60 / 617,655, filed October 13, 2004, U.S. Application 60 / 617,655, filed October 13, 2004 Priority to Application 60 / 617,633 and US Application 60 / 617,670, filed October 13, 2004. All of the aforementioned applications are hereby incorporated by reference in their entirety. Pursuant to 35 U.S.C. §119, this application also claims priority to U.S. Application 60 / 617,653, filed October 13, 2004, and U.S. Application 60 / 624,170, filed November 3, 2004. Filed November 3, 2004 US application 60 / 624,170 filed on . is hereby incorporated by reference in its entirety. This application also fully introduces the international patent application filed on October 13, 2005, with the title of the invention "Compounds for Nonsense Suppression, and Method for Their Use", and the attorney numbers identified as 19025.041, 19025.042, 19025.04...

Claims

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