Normal pressure low oxygen toxicity contaminated system

Abstract

The present invention relates to a normal pressure low oxygen exposure system, which is characterized in that the present invention includes: a box body, which is provided with an air inlet, an air outlet and an open-door; an airflow balance plate which is provided with a plurality of through holes and is arranged in the box body at the end of the air inlet; an oxygen cylinder with the concentration of 10 percent, an outlet of which is provided with a pressure reducing valve and a flowmeter, and the outlet is connected with the air inlet of the box body by a gas pipe; a container containing the substances which can absorb the carbon dioxide and a container containing the substances which can absorb the water vapor, which are respectively arranged in the box body; an oxygen sensor and a carbon dioxide sensor, which are respectively fixed in the box body; a PC mainframe and a display, which are connected mutually and are arranged at the outside of the box body; a signal amplifier, which is respectively connected with the PC mainframe, the oxygen sensor and the carbon dioxide sensor by guide wires. The present invention occupies less space and can monitor the concentrations of the oxygen and the carbon dioxide in the box body at any time, so the present invention can be widely used in the normal pressure and low oxygen exposure process for the preparation of the experimental animal models.

Description

technical field [0001] The invention relates to a drug exposure system, in particular to a normal-pressure hypoxic drug exposure system for preparing experimental animals (rats) hypoxic pulmonary hypertension model and hypercapnia animal model. Background technique [0002] At present, domestic and foreign clinical studies on pulmonary heart disease, cardiovascular and cerebrovascular diseases, pulmonary thromboembolic pulmonary hypertension, and various types of respiratory failure are mainly used to prepare experimental animals (rats) hypoxic pulmonary hypertension models and hypercapnic animals. Model methods and equipment to study a series of organ damage caused by hypoxia and high CO 2 Conditions of organ damage. [0003] Since the late 1980s, the conditions for preparing the above two animal models are very complicated, the site is also large (about 30-40 square meters), and three separate bottles of gas (one bottle of 100% pure oxygen, one bottle of Pure nitrogen an...

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Problems solved by technology

[0003] Since the late 1980s, the conditions for preparing the above two animal models are very complicated, the site is also large (about 30-40 square meters), and three separate bottles of gas (one bottle of 100% pure oxygen, one bottle of Pure nitrogen and a bottle of pure carbon dioxide gas), then install pressure gauges and switches respectively, pass the gas into the box at the same time, estimate the degree of hypoxia in the box according to the gas flow rate (usually the oxygen concentration is 10%), such gas mixture It is not easy to meet the requirements of standardization and scientificity, because the gas flow rate needs to be adjusted frequently, which will easily cause the experiment to fail

In addition, there is no gas balance board in the box, which makes the distribution of hypoxic gas in the box uneven, and will also cause failure in the preparation of related animal models.

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