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Antitussive of Miao national herbs bile prime and method of preparing bile prime

A cough medicine and cholin technology, which is applied in the field of preparation of Miao medicine bilirin cough medicine and cholin, can solve problems such as social harm, and achieve the effects of strong antitussive effect, protection balance, environmental protection, huge social benefit and economic benefit.

Inactive Publication Date: 2011-04-27
贵州百灵企业集团乾元制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the addition of codeine and poppy shells to some cough medicines at present, taking more of them will make the patient become hidden, and the patients will become drug users. The cough medicines that add codeine or poppy shells have become substitutes for drug users at present. cause great harm

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  • Antitussive of Miao national herbs bile prime and method of preparing bile prime
  • Antitussive of Miao national herbs bile prime and method of preparing bile prime
  • Antitussive of Miao national herbs bile prime and method of preparing bile prime

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preparation example Construction

[0011] The preparation method and steps of Miao medicine bile hormone cough medicine of the present invention:

[0012] First wash fresh pig gall or ox gall with water, soak in 75% ethanol for 5 minutes, take it out and dry it, cut the gallbladder, take out the bile, and put it into a 10-ton fermenter; cultivate the Penicillium slant strain at 35±2°C for 6- For 8 days, connect to the first-level seed tank for 40 hours, enter the second-level seed tank for 40 hours, and connect to the fermenter for 5-8 days to prepare the pig gallin or bovine gallin fermented liquid. Compatible organic solvent extraction, repeated 5 times, combined organic solvents, evaporated organic solvents, the extracts were dried, crushed, and passed through 80 mesh sieves to obtain raw material powdered finished bilein.

[0013] Use this bile hormone as raw material to mix with Aodi tea (Miao medicine name: Gabriji), Houttuynia cordata (Miao medicine name: Ruizhu), burdock seed (Miao medicine name: Woxian...

Embodiment 1

[0021] Embodiment 1, first wash fresh pig bile or ox gallbladder with water, soak in 75% ethanol for 5 minutes, take it out and dry it, cut the gallbladder, take out the bile, put it into a 10-ton fermenter; Cultivate at 35±2°C for 6-8 days, connect to the first-level seed tank for 40 hours, enter the second-level seed tank for 40 hours, and connect to the fermenter for 5-8 days to obtain fermented pig gallin or bovine gallin The fermented liquid is extracted with an organic solvent immiscible with water, repeated 5 times, the organic solvent is combined, the organic solvent is evaporated, the extract is dried, pulverized, and passed through an 80-mesh sieve to obtain the raw material powdered finished bilein.

Embodiment 2

[0022] Example 2, first wash fresh pig bile or ox gallbladder with water, soak in 75% ethanol for 5 minutes, take it out and dry it, cut the gallbladder, take out the bile, put it into an enamel plate, about 2 cm thick; insert Qianpenicillium 2000 -1 strain, cultivated in a fermentation room at 35°C-39°C for 15-20 days to obtain a fermented product of porcini or bovine bile, and the fermented product was extracted by adding an organic solvent immiscible with water, repeated 5 times, The organic solvents are combined, evaporated to remove the organic solvents, the extracts are dried, pulverized, and passed through an 80-mesh sieve to obtain the finished bilein in the form of raw materials and powders.

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Abstract

The invention discloses a bilineurin cough-relieving miao medicament, which is prepared from pig's bile or ox bile through inducing Qian penicillin 2000-1 bacterial for fermentation, extracting powdery bile essence, than mixing with ardisia japonica, cordate houttuynia, arctium fruit, root of ballon flower, roor of sessile stemona, isatic root, Sichuan fritillary bulb and auxiliary materials. The invention also discloses the process for preparing the medicament, which has the functions of anti-inflammation for treating cough, sterilizing, resisting viruses, reducing phlegm and relieving cough quickly and effectively. It adopts pig's bile or ox bile as the main content of relieving cough, rather than the snake bile as traditionally used for thousands of years. Therefore, it can prevent from killing in large scale all kinds of snakes protected by country, it is good to protect and balance the ecological environment, and has huge social and economic benefit.

Description

technical field [0001] The invention relates to antitussive medicine, in particular to a Miao medicine bilein cough medicine and a preparation method of bilein. Background technique [0002] Cough is a common disease caused by many factors. In TCM clinical dialectics, it can be divided into cold cough, hot cough, dry cough, and wet cough. Many people with weak physique or serious condition, due to the lack of special effective cough medicine in clinical practice, can't be cured for a long time, protracted time, and eventually become chronic bronchitis or chronic bronchitis. Chronic bronchitis is currently a disease that is difficult to cure. Many patients eventually develop emphysema due to long-term cough, causing cor pulmonale. Due to the addition of codeine and poppy husks to some cough medicines at present, taking more of them will cause the patient to become hidden, and the patients will become drug users. The cough medicines that add codeine or poppy husks have become...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P11/14A61K36/904A61K9/48A61K31/43A61K9/00A61K9/20A61K35/413
Inventor 陈光裕齐茂萍
Owner 贵州百灵企业集团乾元制药有限公司
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