Fluorine ion-releasable composition for dental purposes

A technology of fluoride ions and compositions, applied in dentistry, dental preparations, dental prostheses, etc., can solve the problem of not being able to endow dentin with caries resistance for a long time

Inactive Publication Date: 2008-03-19
KURARAY NORITAKE DENTAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] In the dental material described in Patent Document 1 and the dental resin composition described in Patent Document 2, fluoride ions will be present at several The release is complete in a short period of about a month, so there is a problem that it cannot impart high caries resistance to dentin for a long time

Method used

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  • Fluorine ion-releasable composition for dental purposes
  • Fluorine ion-releasable composition for dental purposes
  • Fluorine ion-releasable composition for dental purposes

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0146]Mix inorganic powder (a1) (15% by weight), 40PMF (10% by weight), 3G (45% by weight), Bis-GMA (28.5% by weight), CQ (0.5% by weight), DMABE (1% by weight) to prepare dental With fluoride ion releasing composition. Then, according to the method described in the following (1), the fluoride ion-releasing property of the dental fluoride ion-releasing composition was examined; according to the method described in the following (2), the dental fluoride ion-releasing composition The acid resistance of the enamel after the substance acts on the enamel. The results are shown in Table 2.

[0147] (1) Fluoride ion release

[0148] Fill the dental fluoride ion-releasing composition into a mold with a diameter of 20 mm and a thickness of 1 mm, and irradiate it with light for 30 seconds with a dental light irradiator (manufactured by Gunma Ushi Sai Electric Co., Ltd., trade name "Rayter II"). This cured product was taken out from the mold and dipped in 10 ml of a phosphate buffer s...

Embodiment 2～8

[0152] Seven dental fluoride ion-releasing compositions with the compositions shown in Table 2 were prepared, and the average fluoride ion release and average calcium ion dissolution were calculated respectively. The results are shown in Table 2.

Embodiment 9～13

[0166] Five dental fluoride ion-releasing compositions with the compositions shown in Table 3 were prepared, and the average fluoride ion release and average calcium ion dissolution were calculated respectively. The results are shown in Table 3.

[0167] [table 3]

[0168] Dental fluoride ion releasing composition

Example 9

Example

10

Example

11

Example

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Example

13

Inorganic powder (a):

Inorganic powder (a6) (weight%)

Inorganic powder (a7) (weight%)

Inorganic powder (a8) (weight%)

Inorganic powder (a9) (weight%)

Inorganic powder (a10) (weight%)

3

-

-

-

-

-

3

-

-

-

-

-

3

-

-

-

-

-

3

-

-

-

-

-

3

Fluoride ion-releasing substance (b):

40PMF (weight%)

10

10

10

10

10

Polymerizable monomer (c):

3G (weight%)

Bis-GMA (weight%)

57 ...

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Abstract

A fluorine ion-releasable composition for dental purposes comprising (a) an inorganic powder, (b) a fluorine ion-releasable substance, (c) a polymerizable monomer and (d) a polymerization initiator, the inorganic powder (a) comprising a complex particle comprising a base particle composed of an inorganic substance and a layer composed of a polysiloxane formed on the surface of the base particle, and the fluorine ion-releasable substance (b) comprising at least one component selected from the group consisting of ammonium fluoride, ammonium hydrogenfluoride, a metal fluoride, a polymer having a vinyl monomer bearing an acid fluoride group as the constitutional unit and a fluorine-containing phosphazene monomer. The composition can provide a high anti-cariogenicity to tooth structure for a prolonged period of time by the action of a fluorine ion released from the composition in a controlled manner. Therefore, the composition can be used suitably as a dental adhesive, a dental filler, a resin for core build-up for dental purposes, a pit and fissure sealant, a dental coating material (manicure), a dental cement or the like.

Description

technical field [0001] The present invention relates to a dental fluoride ion-releasing composition that exhibits a caries-preventing effect through the dentin strengthening action of fluoride ions. The dental fluoride ion-releasing composition of the present invention can exert the effect of preventing dental caries for a long time, so it can be used as a dental adhesive material, a dental filling material, a resin for dental scaffold construction, a pit and fissure sealing material, and a dental coating material ( It is particularly useful for dental materials such as dental cement. Background technique [0002] It is well known that fluoride ions strengthen dentin, and dental materials containing fluoride ion-releasing substances have been used to prevent and suppress dental caries. [0003] For example, the following Patent Document 1 describes a dental material containing a homopolymer of (meth)acryloyl fluoride or a copolymer of (meth)acryloyl fluoride and a lower alk...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K6/08A61K6/00A61K6/884
CPCA61K6/093A61K6/083A61K6/896A61K6/887A61P1/02C08L83/04C08L33/00A61K6/00
Inventor 武井满北广敬大原康次郎
Owner KURARAY NORITAKE DENTAL
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