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Novel antidiabetic

An anti-diabetic and new drug technology, applied in the field of medicine, can solve the problems of high price and strong drug resistance, and achieve the effect of lowering blood sugar level, improving glucose tolerance, and strong synergistic anti-diabetic effect.

Inactive Publication Date: 2008-06-25
邱日辉 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Insulin, sulfonylureas, and biguanides used to treat diabetes have obvious hypoglycemic effects, but they have many side effects, are expensive, and have strong drug resistance.

Method used

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  • Novel antidiabetic
  • Novel antidiabetic

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] 1. Ingredients: Fenbaicao: 50 grams

[0024] Tea leaves: 50 grams

[0025] 2. Preparation:

[0026] Wash the freshly collected P. chinensis growing in Hubei Province, dry in the sun, slice and crush, crush and sieve to 25-50 mesh. Take 50 grams of crushed Herba Vernis and soak in 3000 ml of distilled water for 0.5 hours, then boil it for 30 minutes, then slowly cool down to room temperature and keep it for 3 hours and extract it in the usual way. After the extraction is completed, pass through 8 layers of gauze Filter and remove the herbaceous residue to obtain 2000 ml of filtrate. Then soak 50 grams of tealeaves with 2000 milliliters of filtrate at 4°C for 10 hours, and filter the tea leaves with 2 layers of gauze after the extraction is completed. The resulting filtrate was subjected to vacuum freeze-drying at -140° C. to obtain 1 gram of dry powder of the antidiabetic original drug of the present invention. The dry powder of the antidiabetic original dru...

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Abstract

The invention belongs to the field of medicine, in particular to a new drug for anti-diabetes, which takes a wild plant discolorous clinquefoil root and tea as the raw materials, the wild plant discolor cinquefoil herb and the tea are in the proportion of 1 to 1 through 1 to 10 or 10 to 1, producing the material powder through 8 steps, resloving in the normal saline to get the oral liquid of the new drug for anti-diabetes. The material powder can be produced with the medical carrier or excipient to troche, water agent, capsule, drop pills for anti-diabetes by tradtional method. The oral liquid is applied to animal test to prove that the oral liquid can reduce the food quantity, weight, the content of blood sugar and glycosylation haematoglobin in the blood of tested II-type diabetes mouse induced by the streptozotocin, increase the tolerance of the grape sugar and reduce the blood sugar level of the I-type diabetes mouse induced by the tetraoxypyrimidine.

Description

Technical field: [0001] The invention belongs to the field of drugs, in particular to a new antidiabetic drug. Background technique: [0002] Diabetes mellitus is due to the interaction of genetic and environmental factors, resulting in the absolute or relative insufficiency of insulin secretion and the decrease in the sensitivity of target tissue cells to insulin, causing a series of metabolic disorder syndromes such as protein, fat, water and electrolytes, among which hyperglycemia is the main symbol . Typical clinical cases may show symptoms such as polyuria, polydipsia, polyphagia, and weight loss, that is, symptoms of "three excesses and one deficiency". Diabetes is one of the most common chronic diseases. With the improvement of people's living standards, the aging population and obesity rate The incidence of diabetes is increasing year by year. The incidence rate of diabetes in China reaches 2%. According to statistics, there are 40 million diagnosed diabetic patien...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/82A61K9/08A61K9/10A61K9/14A61K9/20A61K9/48A61P3/10
Inventor 张南
Owner 邱日辉
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