Conversion of amorpha-4,11- diene to artemisinin and artemisinin precursors
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- AMYRIS BIOTECHNOLOGIES INC (US)
- Publication Date
- 2008-06-25
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
[0001] Cross References to Related Applications
[0001] This application claims U.S. Provisional Patent Application No. 60 / 685,713, filed May 27, 2006; U.S. Provisional Patent Application No. 60 / 775,517, filed February 21, 2006; and U.S. Patent Application No. 11, filed May 23, 2006 / 419,975 priority, which are hereby incorporated by reference in their entirety for all purposes. Background of the invention
[0002] About 270 million people are infected with malaria, making it one of the world's leading infectious diseases. The development of new anti-malarial drugs, and alternative methods of producing anti-malarial drugs, is therefore an important worldwide health goal.
[0003] One of these antimalarial drugs is artemisinin (compound 4 in Table 1). Artemisinin is a component of the traditional Chinese herbal medicine Artemisia annua, which has been used in China for more than 1000 years to control fever symptoms. In the scientific literature, artemisinin is also sometime...