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Ivermectin compound plant source pesticide and preparing method thereof

A plant-derived insecticide, ivermectin technology, applied in botanical equipment and methods, plant growth regulators, biocides, etc., can solve the problem of parasitic diseases and drug resistance, offset azadirachtin Environmental protection effect, insecticidal performance is not as good as before, etc., to achieve the effect of low cost, low environmental pollution, and wide insecticidal spectrum

Inactive Publication Date: 2008-07-23
BEIJING DAWEIJIA BIOTECH SHARE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, ivermectin has caused drug resistance in aquatic animals due to its wide use and preparation, and its insecticidal performance is not as good as before; plant-derived insecticides, such as azadirachtin, matrine, and arecoline, have safe use. , no drug residues, are recognized as pollution-free insecticides, but these drugs degrade quickly in the use environment, unstable performance, high cost of use and difficult to promote on a large scale, such as the solvent and co-solvent of azadirachtin are mostly Benzene, which pollutes the environment greatly, offsets the environmental and ecological protection effect of azadirachtin
Therefore, a single, simple parasite insecticide can no longer solve the problem of parasitic diseases and drug resistance in aquaculture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The preparation of ivermectin and botanical insecticide microemulsion comprises the steps:

[0032] (1) Ivermectin (produced by Shandong Qifa Pharmaceutical Co., Ltd., the same below) 0.1%, neem oil (produced by Luxi Guangming Neem Development Company) 1%, matrine (produced by Baoji Fangsheng) in proportion Development Co., Ltd.) 0.1%, betel nut extract (Shifang Jubang Plant Raw Materials Co., Ltd.) 3% were added to 15% ethanol for dissolution to obtain the original medicinal solution;

[0033] (2) Mix the emulsifier composed of 10% Tween 80 and Span 80 (the ratio of both is 5: 1), 6% azone and 2% 3-chloro-1,2-propylene oxide , adding 60.8% distilled water to obtain a mixed solution;

[0034] (3) Heat the mixed solution to 50-60°C, and stir to make it into a uniform liquid, then add the original drug solution prepared in step (1) into the mixed solution under stirring, when the phase inversion becomes a homogeneous phase, translucent or When it is a transparent liquid...

Embodiment 2

[0036] The sources of raw materials and the preparation method are the same as those in Example 1. The components and their proportions are: ivermectin 0.25%, neem oil 0.5%, matrine 0.15%, betel nut extract 5%, methanol 15%, 700# 10%, azone 6%, epoxidized soybean oil 1%, glycerol 1%, and the balance is 61.1% distilled water.

Embodiment 3

[0038] The sources of raw materials and the preparation method are the same as those in Example 1. The components and their proportions are: 0.5% ivermectin, 0.25% neem oil, 0.1% matrine, 5% betel nut extract, 15% ethanol, OP-10 10%, also oxidized linseed oil 2%, azone 6%, ethylene glycol 2%, the balance is 59.15% of distilled water.

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PUM

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Abstract

The invention discloses an ivermectin composite botanical pesticide which mainly comprises 0.05 to 5 percent of ivermectin, 0.05 to 20 percent of azadirachtin, 0.01 to 5 percent of matrine, 0.01 to 5 percent of arecoline and auxiliary agents. The invention is mainly applied to the prevention of parasites on the body surface of aquatic animals and has the advantages of high pesticide effect, broad pesticide spectrum, low irritation on aquatic animals, low cost, environmentally friendliness, etc.

Description

technical field [0001] The invention belongs to an insecticide for aquatic animals, in particular to an ivermectin compound plant-source insecticide and a preparation method thereof. Background technique [0002] With the rapid development of aquaculture in my country, the total amount of aquatic products in my country has ranked first in the world for many years, but aquatic animal diseases are also increasing and mutating year by year, which brings great hidden dangers to the health of aquaculture. Every year, the parasites of aquatic animals: trichomonas, melon worms, ring worms, third-generation worms, Chinese fleas, anchor head fleas and other diseases have caused great economic losses to the aquaculture industry. In the prevention and treatment of aquatic animal parasitic diseases, drugs such as dichlorvos, acephate, malachite green, and mercurous nitrate have been eliminated due to their poor safety, environmental pollution, and harm to human health. At present, chem...

Claims

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Application Information

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IPC IPC(8): A01N43/24A01N43/42A01N43/12A01N43/40A01P7/00
Inventor 蔡泽文伍冶胡兴平谢碧文
Owner BEIJING DAWEIJIA BIOTECH SHARE CO LTD