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Compound kanamycin sulphate injection for dogs and preparation thereof

A technology of kanamycin sulfate and kanamycin monosulfate, which is applied in the field of compound kanamycin sulfate injection for dogs and its preparation, can solve the problems of decreased resistance, prolongation of disease and secondary infection in sick dogs, etc. Achieve the effects of restoring appetite, relieving pain, and preventing secondary infection

Inactive Publication Date: 2010-06-09
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Canine parainfluenza is a respiratory disease of dogs. The pathogen is canine parainfluenza virus. The clinical manifestations mainly include elevated body temperature, serous fluid from the nostrils, mucus, and even purulent nasal fluid. Sick dogs have severe cough, lack of energy, and decreased appetite. The condition improved after a week, but due to the decline of the sick dog's resistance, it is easy to cause other secondary infections, prolong and aggravate the condition, and even lead to death
There is currently no specific drug for canine parainfluenza

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] (1) Take 5 billion units of kanamycin monosulfate, put it into 40L of water for injection, then add 1-10kg of fosfomycin sodium and 20kg of analgin, and stir until completely dissolved.

[0022] (2) Take 10L of water for injection, add 0.2kg of sodium bisulfite and 0.01kg of EDTA-2Na, and stir until completely dissolved.

[0023] (3) Take 30kg of propylene glycol and heat to dissolve 0.1kg of doxofylline.

[0024] (4) Combine the solutions prepared in step 1, step 2, and step 3, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the compound kana sulfate for dogs of the present invention after the medicinal liquid is clear Mycin Injection.

Embodiment 2

[0026] (1) Take 20 billion units of kanamycin monosulfate, put it into 40L of water for injection, then add 10kg of fosfomycin sodium and 20kg of analgin, and stir until completely dissolved.

[0027] (2) Take 10 L of water for injection, add 0.2 kg of sodium bisulfite and 0.01 kg of EDTA-2Na, and stir until completely dissolved.

[0028] (3) Take 30kg of propylene glycol and heat to dissolve 2kg of doxofylline.

[0029] (4) Combine the solutions prepared in step 1, step 2, and step 3, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the compound kana sulfate for dogs of the present invention after the medicinal liquid is clear Mycin Injection.

Embodiment 3

[0031] (1) Take 7 billion units of kanamycin monosulfate, put it into 40 L of water for injection, then add 8 kg of fosfomycin sodium and 20 kg of analgin, and stir until completely dissolved.

[0032] (2) Take 10 L of water for injection, add 0.2 kg of sodium bisulfite and 0.01 kg of EDTA-2Na, and stir until completely dissolved.

[0033] (3) Take 30kg of propylene glycol and heat to dissolve 1.5kg of doxofylline.

[0034] (4) Combine the solutions prepared in step 1, step 2, and step 3, then add water for injection to 100L, stir evenly, keep for 15-20min, and make the compound kana sulfate for dogs of the present invention after the medicinal liquid is clear Mycin Injection.

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PUM

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Abstract

The invention discloses a compound kanamycin sulfate injection for dogs and a preparation method thereof, which aims at providing the compound kanamycin sulfate injection that has rapid onset of action for the treatment for canine parainfluenza and can ease the clinical reactions of the affected dogs, reduce the times and the dosage of the drug administration, alleviate the suffering of the dogs and the difficulty of the treatment operation, and the preparation method that has simple process and easy realization. Each 100l injection contains: 5 to 20 billion units of kanamycin monosulfate, 1 to 10kg of fosfomycin sodium, 0.1 to 2kg of doxofylline, 20kg of analgin, 0.2kg of sodium bisulfite, 0.01kg of EDTA-2Na, 30kg of propylene glycol and the rest of water for injection. The injection of the invention is a compound preparation which combines antibiotics and drugs for the symptomatic treatment for usage, thus having rapid onset of action for the treatment for canine Para influenza and being able to ease the stress reactions of the affected dogs, prevent the secondary infection and accelerate the recovery of the dogs.

Description

technical field [0001] The invention relates to a compound kanamycin sulfate injection for dogs and a preparation method thereof. Background technique [0002] Canine parainfluenza is a respiratory disease of dogs. The pathogen is canine parainfluenza virus. The clinical manifestations mainly include elevated body temperature, serous fluid from the nostrils, mucus, and even purulent nasal fluid. Sick dogs have severe cough, lack of energy, and decreased appetite. The condition improved a week later, but due to the decline in the resistance of the sick dog, it is easy to cause other secondary infections, prolong and aggravate the condition, and even lead to death. There is currently no specific drug for the treatment of canine parainfluenza. Contents of the invention [0003] The purpose of the present invention is to overcome the deficiencies in the prior art, to provide a kind of canine parainfluenza that can be treated symptomatically, and can control the secondary infe...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/7036A61K31/662A61K31/52A61K31/4152A61P11/00A61P31/12
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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