Novel use of staphylococcus enterotoxin A gene

A staphylococcal intestinal and gene technology, which can be used in gene therapy, medical preparations containing active ingredients, antiviral agents, etc., and can solve problems such as weak immunogenicity
CN101297967AInactive Publication Date: 2008-11-05INST OF BIOENG ACAD OF MILITARY MEDICAL SCI OF THE CHINESE
2 Cites 2 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF BIOENG ACAD OF MILITARY MEDICAL SCI OF THE CHINESE
Publication Date
2008-11-05
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
Patent Text Reader

Abstract

The invention discloses a new use of staphylococcal enterotoxin gene A. An experiment carried out by the author of the invention shows that the staphylococcal enterotoxin gene A can obviously improve the reactivity of animals to DNA vaccines and can be used as an adjuvant for improving the immunogenicity of the DNA vaccines or recombinant subunit vaccines. The staphylococcal enterotoxin gene A can improve the immunogenicity of various DNA vaccines, such as HBV surface antigen DNA vaccine and malaria multi-epitope antigen DNA vaccine, etc., has broad spectrum, and is a rare adjuvant for improving the immunogenicity of the DNA vaccines. Therefore, the staphylococcal enterotoxin gene A has great significance in the production and the application of the DAN vaccines and the recombinant subunit vaccines.
Need to check novelty before this filing date? Find Prior Art

Description

[0001] This application is a divisional application with the application number 200510068114.0, the application date is April 26, 2005, and the invention creation title is "New Application of Staphylococcal Enterotoxin A Gene and Its Encoded Protein". technical field

[0002] The present invention relates to a new application of the staphylococcal enterotoxin A gene and its encoded protein, in particular to the use of the staphylococcal enterotoxin A gene as an adjuvant for enhancing the immunogenicity of DNA vaccines and the encoded protein of the gene as a recombinant subunit for enhancing the immunogenicity Use in adjuvants. Background technique

[0003] Staphylococcal enterotoxin A (staphylococcal enterotoxin A, SEA) is a member of the staphylococcal enterotoxin family produced by Staphylococcus aureus and is one of the most effective T cell activating factors. SEA is a protein molecule containing 233 amino acid residues, rich in serine (S), threonine (T) and aspartic ac...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More