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Polypeptide calcium and use

A technology of peptide calcium and application, applied in the field of calcium nutrition fortifier, can solve the problems of low activity, long absorption and utilization time, etc., and achieve the effect of long metabolism time, strong activity and diversity, and improving absorption efficiency

Inactive Publication Date: 2008-11-19
李绍通
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The average molecular weight of calcium polyaspartate is above 8000, the human body absorbs and utilizes it for a long time, and its activity is small

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Regeneration and washing of cation-exchange resin: the ion-exchange column equipped with 2 kg of cation-exchange resin is regenerated with high-quality hydrochloric acid (concentration 4-6%), and then washed to neutrality with pure water.

[0023] Pass 100 grams of polyaspartic acid salt solution (15% polyaspartic acid content) with an average molecular weight of 1000-5000 through an ion exchange column to remove cations in the solution to obtain a catalyst solution for the synthesis reaction.

[0024] Take 50 grams of the above-mentioned catalyst solution and 120 grams of L-aspartic acid and mix them evenly, and put them into a light wave microwave reactor.

[0025] React in a light wave microwave reactor for 12-18 minutes, and polymerize into about 100 grams of polypeptide intermediates.

[0026] Add 100 grams of polypeptide intermediates to 200 grams of pure water, and slowly add powdered pharmaceutical grade calcium oxide under stirring to make them react to form po...

Embodiment 2

[0029] Regeneration and washing of cation-exchange resin: the ion-exchange column equipped with 3 kg of cation-exchange resin is regenerated with high-quality hydrochloric acid (concentration 4-6%), and then washed to neutrality with pure water.

[0030] Pass 200 grams of aspartic acid glutamic acid copolymer salt solution (copolyaspartic acid glutamic acid content 18%) with an average molecular weight of 1000-5000 through an ion exchange column to remove cations in the solution to obtain a catalyst for the synthesis reaction solution.

[0031] Take 60 grams of the above catalyst solution, mix them evenly with 130 grams of L-aspartic acid and 20 grams of L-glutamic acid, and put them into a light wave microwave reactor.

[0032] React in a light wave microwave reactor for 12-18 minutes, and polymerize into about 130 grams of polypeptide intermediates.

[0033] Add 100 grams of polypeptide intermediates to 200 grams of pure water, slowly add powdered edible calcium carbonate u...

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PUM

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Abstract

A polypeptide calcium serving as calcium nutrition enhancer is prepared from a polypeptide intermediate obtained by copolymerizing aspartic acid or aspartic acid and glutamic acid as a raw material by reacting with edible calcium carbonate or calcium oxide (pharmaceutical grade). The polypeptide calcium contains polypeptide calcium with chemical activity, which has a molecular weight less than 1,000 and can be directly absorbed by human body, and chemical polypeptide calcium with a molecular weight of 3,000 to 5,000, which can be absorbed by human body at slower speed and has longer metabolism time. The polypeptide calcium can be sufficiently absorbed by human body, and is a green and environment-friendly calcium nutrition enhancer with wide application prospect.

Description

technical field [0001] The invention relates to a polypeptide calcium used as a calcium nutrition enhancer. technical background [0002] "Peptide is a compound in which two or more amino acids are connected by peptide bonds." Amino acids must be connected by peptide bonds to form "amino acid chains" and "amino acid strings". Only "chained amino acids" can be called peptides. A compound in which two amino acids are connected by a peptide bond is called a dipeptide, a compound in which three amino acids are connected by a peptide bond is called a tripeptide, and so on, there can be dozens of peptides. [0003] Amino acid chains can be divided into "short chain" and "long chain". The short chain is generally composed of 26 amino acids, and the long chain is generally composed of more than 10 amino acids. The molecular weight of amino acid short-chain peptides is generally below 1000. It has strong activity and diversity. It can be directly absorbed without digestion. After en...

Claims

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Application Information

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IPC IPC(8): A23L1/304A23L1/305A23L33/16A23L33/18
Inventor 李绍通
Owner 李绍通
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