Special shape tissue engineering bracket and construction method and use thereof

A tissue engineering scaffold and a technology with a specific shape, which are applied in the field of tissue engineered cartilage preparation, can solve problems such as being unfavorable for industrialized production, complex modeling of an all-external nose model stent, and unfavorable for the construction of bone marrow stromal stem cells, etc.
CN101361682AInactive Publication Date: 2009-02-11SHANGHAI TISSUE ENG LIFE SCI
0 Cites 25 Cited by

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI TISSUE ENG LIFE SCI
Publication Date
2009-02-11
Estimated Expiration
Not applicable · inactive patent

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses a method for in vitro establishment of special-shaped tissue engineering scaffolds, comprising steps as follows: (1) applying computer aided design to establish a digital model for special-shaped tissues or organs; (2) guiding the digital model acquired in the step (1) into a rapid prototyping machine for processing, to shape a solid female die for the special-shaped tissues; (3) adding biodegradable materials acceptable by the medical science into the solid female die gained in the step (2), to acquire a special-shaped tissue engineering scaffold. The special shapes are chosen according to the shapes of auricle, external nose, nose prosthesis, chin prosthesis and other human issues or organs. The special-shaped tissue engineering scaffold can be effectively compounded with the chondrocytes to finally form special-shaped tissue engineering cartilages. The invention also provides a detailed method of preparing tissue engineering auricle and external nose scaffolds and application thereof.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the fields of medicine and biomedical engineering, and more particularly to a preparation method and application of tissue-engineered cartilage applied in the field of craniomaxillofacial surgery of plastic surgery. Background technique

[0002] The defect or loss of the outer ear caused by congenital microtia, trauma, or tumor is relatively common in clinical practice; the current treatment method is mainly to excise the autologous costal cartilage, and sculpt it to reconstruct the affected ear; however, there are different shapes in different degrees. , secondary defects and other issues. The defect or loss of the external nose due to congenital external nasal deformities, trauma, and tumors is relatively common in clinical practice; the current treatment methods are mainly the use of frontal pedicled flaps and postauricular island flaps with superficial temporal postauricular vascular pedicles. , forearm leather tube, and m...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More