Asiatic centella extract and preparation methode thereof

A Centella asiatica extract and extract technology are applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve problems such as being unsuitable for industrial large-scale production, achieve controllable product quality, reduce physical and mental damage, and low production cost Effect

Active Publication Date: 2009-04-01
TIANJIN TASLY MORDEN TCM RESOURCES
View PDF0 Cites 14 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Not suitable for large-sc

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Asiatic centella extract and preparation methode thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Example 1 Preparation method of extract

[0075] Centella asiatica herbal material is crushed into coarse powder, extracted with 60% ethanol and refluxed twice for 2 hours each time. The amount of 60% ethanol for the first time is 10 times that of the medicinal material, and the second time is 8 times. Filter, combine the filtrate, and add 0.2% activated carbon is refluxed for 30 minutes to decolorize, filter while hot, and concentrate under reduced pressure to recover ethanol to a thick extract without alcohol. The thick extract is adjusted with water to 3:1 (volume and amount of medicinal materials) liquid, filtered, and on the filtrate AB-8 resin adsorption, eluted with 4 column volume of water, 20% ethanol, 30% ethanol, 6 column volume of 40% ethanol, 4 column volume of 50% ethanol, and collected 30% respectively. , 40%, 50% ethanol elution part, the three eluates are concentrated under reduced pressure to a specific gravity of 1.10-1.15, and dried under reduced pressur...

Embodiment 2

[0076] Example 2 Preparation method of extract

[0077] Centella asiatica herbal material was crushed into coarse powder, extracted with 10% ethanol and refluxed twice for 3 hours each time. The amount of 10% ethanol for the first time was 10 times that of the medicinal material, and the second time was 8 times. Filtered, combined the filtrate, and added 0.2% activated carbon is refluxed for 20 minutes to decolorize, filter while hot, and concentrate under reduced pressure to recover ethanol to a thick extract without alcohol. The thick extract is adjusted with water to 2:1 (volume and amount of medicinal material) medicinal solution, filtered, and on the filtrate AB-8 resin adsorption, eluted with 4 column volume of water, 20% ethanol, 30% ethanol, 6 column volume of 40% ethanol, 4 column volume of 50% ethanol, and collected 30% respectively. , 40%, 50% ethanol elution part, the three eluates are concentrated under reduced pressure to a specific gravity of 1.10-1.15, and dried un...

Embodiment 3

[0078] Example 3 Preparation method of extract

[0079] Centella asiatica is crushed into coarse powder, extracted with 95% ethanol and refluxed once for 3 hours each time. The amount of 95% ethanol for the first time is 6 times that of medicinal materials, and the second time is 12 times. Filter, combine the filtrate, and add 0.2% activated carbon is refluxed for 40 minutes to decolorize, filter while hot, and concentrate under reduced pressure to recover ethanol to a thick extract without alcohol. The thick extract is adjusted to a 3:1 (volume and amount of medicinal material) medicinal solution (volume and amount of medicinal material) by adding water, filtered, and on the filtrate AB-8 resin adsorption, eluted with 4 column volume of water, 10% ethanol, 20%, 30% ethanol, 6 column volume of 40% ethanol, 4 column volume of 50% ethanol, 2 Elute with 90% ethanol in multiples, collect 10%, 20%, 30%, 40%, 50%, 90% ethanol elution fractions, and concentrate the five eluates under red...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses an Asiatic pennywort herb extract and a preparation method thereof. The rough powder of Asiatic pennywort herb is taken to be extracted, filtered and decolorized by hydrous ethanol reflux and to be condensed into extract; the extract is solved by water to obtain a liquid medicine; the liquid medicine is put upon a resin column and is processed for gradient elution sequentially by hydrous ethanol to collect eluant with different concentrations respectively; and the eluant is condensed and dried to obtain the extract. The method has simple operation, low cost and stable extract content and is fit for the industrialized production.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine extract, in particular to an extract of Centella asiatica and a preparation method thereof. Background technique [0002] Centella asiatica (L.) Urb. (Hydrocotyle asiatica L.), umbelliferous plant, also known as Desmodium vulgare, Beng Dawan, Liaowan grass, horseshoe grass, Gotu Kola, cricket shell, coin grass, It's too late to beat, and eighteen deficiencies. The whole herb is used as medicine to clear away heat and dampness, detoxify and reduce swelling. Used for damp-heat jaundice, heatstroke, diarrhea, sand and blood, carbuncle, swelling and sore toxins, fall and flutter injury. The chemical constituents of Centella asiatica are mainly triterpenoids, such as asiaticoside, madecassoside hydroxy, boremoside, boremiside, ginsenoside, isosinicumin, etc. Terpene ester glycosides. Centella asiatica also contains some triterpene acids, such as Asiatic acid, Asiatic acid, Portomic acid, Asiatic acid, etc. ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/23A61P1/12A61P1/16A61P17/02A61P43/00
Inventor 刘顺航闫立萍马素珍王平刘岩周福军
Owner TIANJIN TASLY MORDEN TCM RESOURCES
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap