Swertia diluta extract and preparation method and use thereof
A medicinal extract and extract technology are applied in the field of medicinal extract and its preparation and application, which can solve the problems of difficulty in extraction and purification, few literatures, and weak functional group specificity, so as to improve the curative effect of medicine, easy to operate, and reliable. Strong implementation effect
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0020] Take 10Kg of medicinal materials, cut them into pieces by 2-5 cm, add 120L of water, soak for 1 hour, reflux extraction for 1 hour, filter; add 100L of water to the dregs, reflux extraction for 1 hour, filter, and extract the dregs once more in the same way. Combine the filtrates, concentrate until the volume ratio of the medicinal solution to the medicinal material is 2:1, and centrifuge at 4000rpm for 10min. Get the supernatant and add it to the processed HPD300 (Cangzhou Baoen Chemical Co., Ltd.) macroporous adsorption resin column (the volume of the resin bed is about 33L, which is equivalent to the weight ratio of dry resin and medicinal material being 0.75:1, and the diameter-to-height ratio 1:7), first use 3 times the volume of the resin bed (3BV) for water elution to almost colorless, discard the eluent, and then elute with 25% aqueous ethanol, collect 1 part per 7500ml, collect 16 parts (equivalent to about 4BV), test, according to the test results, decide to c...
Embodiment 2
[0023] Take 6Kg of the medicinal material, crush it properly, add 72L of water, soak for 1 hour, reflux for 1 hour, filter; add 60L of water to the dregs, reflux for 1 hour, filter, extract the dregs again in the same way, combine the filtrate, and concentrate Until the volume of the medicinal liquid and the mass ratio of the medicinal material are 2:1, filter, get the filtrate, and add it to the processed HPD100 (Cangzhou Baoen Chemical Co., Ltd.) type macroporous adsorption resin column (resin bed volume 24L, which is equivalent to dry resin and The weight ratio of the medicinal material is 0.9:1, and the diameter-to-height ratio is 1:5), first wash and elute with water twice the resin bed volume (2BV), discard the eluent, and then elute with 40% ethanol aqueous solution, Collect 1 fraction per 6000ml, collect up to 16 fractions (equivalent to about 4BV), test, decide to combine the 2nd to 13th fractions of eluents according to the test results, and recover ethanol under redu...
Embodiment 3
[0026] Take 2Kg of medicinal materials, cut into pieces 2-5 cm, add 24L of water, soak for 1 hour, reflux extraction for 1 hour, filter; add 20L of water to the dregs, reflux extraction for 1 hour, filter, and extract the dregs once more in the same way, Combine the filtrates, concentrate until the volume of the medicinal liquid and the mass ratio of the medicinal materials are 2:1 (v / w), filter, take the filtrate, and add it to the D101 (Tianjin Haiguang Chemical Co., Ltd.) type macroporous adsorption resin column (resin Bed volume 6L, equivalent to the weight ratio of dry resin and medicinal material is 0.6: 1, the ratio of diameter to height is 1: 6), first use 4 times of resin bed volume (4BV) water elution, discard eluent, Then elute with 60% ethanol aqueous solution, collect 1 part per 1500ml, collect to 16 parts (equivalent to about 4BV), detect, and decide to combine the 2nd to 12th eluents according to the test results, and recover ethanol under reduced pressure at 60°...
PUM
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com