Production method of high-content beta-sitosterin

Abstract

The invention relates to a method for producing high-content Beta-sitosterin, which comprises the steps that: deodorized distillate of vegetable oil containing 4 percent to 7 percent of Beta-sitosterin is taken as the raw material and goes through the processes of esterification, alcoholysis, short-range separation, cold setting, filtering, washing of filter cakes, vacuum drying and the like. The method has the advantages that: (1) the high-content Beta-sitosterin (with the content higher than 80 percent) can be prepared directly from the deodorized distillate of the vegetable oil, thereby avoiding the complex processes that mixed phytosterin is obtained from the deodorized distillate of the vegetable oil and then purified and separated to obtain Beta-sitosterin, and creating great industrial productive value and social benefits; (2) the method uses a special non-toxic organic solvent and appropriate process conditions, thus greatly improving the purity and yield of the Beta-sitosterin and resulting in no environmental pollution; and (3) other by-products and solvents can be recycled, thereby fully utilizing resources and reducing production cost.

Description

technical field [0001] The invention relates to a production method of high-content β-sitosterol. Background technique [0002] β-sitosterol (β-sitosterol) widely exists in the fruits and seeds of various plants, and also exists in various vegetables and fruits. It forms a mixture with brassicasterol, campesterol, and stigmasterol. β-sitosterol can inhibit the absorption of cholesterol by the human body, promote the biochemical synthesis of cholesterol, and reduce cholesterol, while other phytosterol components have no value in inhibiting the absorption of cholesterol. Therefore, the content of β-sitosterol as a drug raw material must be more than 80%. At present, the mixed phytosterols on the market contain about 40% β-sitosterol. Due to the extremely similar molecular structure and physical and chemical properties, it is a comparison to separate 80% monomeric β-sitosterol with a higher purity. Difficult and cumbersome work, there is no mature production method of more th...

AI Technical Summary

Problems solved by technology

At present, the mixed phytosterols on the market contain about 40% β-sitosterol. Due to the extremely similar molecular structure and physical and chemical properties, it is a comparison to separate 80% monomeric β-sitosterol with a higher purity. Difficult and cumbersome work, there is no mature production method of more than 80% β-sitosterol at home and abroad