Medical components having coated surfaces exhibiting low friction and methods of reducing sticktion

A technology of inner surface and outer surface, applied in other medical devices, coatings, medical science, etc., can solve problems such as high starting and/or loosening force, incomplete effectiveness, expensive materials, etc.

Active Publication Date: 2009-09-09
BECTON DICKINSON & CO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] Silicone oils are also commonly used as lubricants and are not prone to oxidation, but migration and sticking do occur and high breakout and / or breakout forces are a problem
Teflon surfaces provide some drop in breakout and / or breakout force, but this material is very expensive, and the method is not entirely effective

Method used

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  • Medical components having coated surfaces exhibiting low friction and methods of reducing sticktion
  • Medical components having coated surfaces exhibiting low friction and methods of reducing sticktion
  • Medical components having coated surfaces exhibiting low friction and methods of reducing sticktion

Examples

Experimental program
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Effect test

Embodiment approach

[0085] The coated chamber and / or the coated sealing element is subjected to an oxidation treatment, eg plasma treatment. Plasma treatment can be performed in any common vacuum or atmospheric plasma generating equipment. Any suitable ionizing plasma may be used, such as plasma generated by glow discharge or corona discharge. Plasma can be generated from various gases or mixtures thereof. Commonly used gases include air, hydrogen, helium, ammonia, nitrogen, oxygen, neon, argon, krypton, and xenon. Any gas pressure may be used, such as atmospheric pressure or less than or equal to 5 mmHg, such as about 0.1 to about 1.0 mmHg. In some embodiments, such as atmospheric oxidation methods, the ionized plasma is introduced directly within the chamber through a small port or an opening that is subsequently sealed by a sealing element. The outer surface of the coated sealing element can be treated directly similar to corona or plasma treatment methods. In other embodiments, such as va...

Embodiment

[0098] Syringe barrels of 10 and 50 ml syringes were coated with the coating composition of the present invention. Syringe barrels were formed from cyclic polyolefin, and the inside surface of each barrel was coated with DC360 dimethicone, viscosity 12,500 cst, available from Dow Corning. Pretreat selected barrels with argon plasma from the injection end of the barrels for the time periods specified in Table 1. Plasma treatment was performed using a conventional atmospheric pressure plasma treatment apparatus as described above.

[0099] Helvoet FM460 (Butyl-A) and FM457 (Butyl-B) butyl rubber and Kokoku SBR syringe stoppers were coated with conventional polydimethylsiloxane with a viscosity of 100,000 cst.

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PUM

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Abstract

This invention relates to components useful for medical articles, such as a syringe assembly, having sliding surface(s) coated with a composition including organopolysiloxane(s), the coating being adhered to the surface(s) of the component by crosslinking induced by oxidative treatment and irradiation with an isotope, electron beam or ultraviolet radiation or heat treatment; medical articles including the same; methods to reduce static and kinetic friction between slidable surfaces; and articles of low friction prepared thereby.

Description

technical field [0001] The present invention relates to medical components having surfaces coated with organopolysiloxane-containing compositions in sliding engagement devices, such as syringe components, and to methods of reducing static and dynamic friction between slidable surfaces, and consisting of Low-friction products prepared by it. Background technique [0002] Some devices require slow and controlled initiation and maintenance of sliding movement of one surface over the other. It is well known that two stationary surfaces in a sliding relationship often exhibit sufficient resistance to initial movement, so that gradually increasing force applied to one of the surfaces causes no movement until a threshold force is reached, at which point a sudden sliding or shear separation of the surfaces occurs . The sudden separation of this stationary surface into a sliding relationship is referred to herein as "breakout" or "breakloose". [0003] "Cracking force" refers to t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/10A61L31/14
CPCA61M5/31513A61M2005/3131A61L31/10A61M2207/00A61L31/14
Inventor S-R·吴A·奥瓦勒兹小S·西蒙斯
Owner BECTON DICKINSON & CO
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