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Chinese medicinal composition for treating pulmonary interstitial fibrosis

A technology of composition and traditional Chinese medicine components, which is applied in the field of traditional Chinese medicine compositions, can solve problems such as pulmonary interstitial fibrosis, low success rate of lung organ transplantation, and inability of patients to receive treatment, etc. The effect of volume reduction and convenient administration

Inactive Publication Date: 2009-09-30
BEIJING NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the level of economic development in my country is relatively low. Even effective cytokine therapy for pulmonary fibrosis is too expensive for most patients to receive treatment.
Some foreign scholars have tried to use lung transplantation to treat pulmonary fibrosis. Regardless of the economic cost, the success rate of lung organ transplantation is low, which cannot solve the problem of pulmonary interstitial fibrosis.

Method used

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  • Chinese medicinal composition for treating pulmonary interstitial fibrosis
  • Chinese medicinal composition for treating pulmonary interstitial fibrosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0095] The prescription of the composition of the present invention:

[0096] Cordyceps mycelium 42g Breviscapus 317g Notoginseng 317g Salvia 317g

[0097] Rhodiola 211g Ginkgo biloba 211g Chuan Fritillaria 127g Leeches 32g

[0098] Anemarrhena 127g Dilong 32g

[0099] Preparation:

[0100] Take the above ten flavors, take Cordyceps mycelium, earthworm and leech, and crush them into fine powder, and set aside; take another seven flavors, such as erigeron breviscapita, Panax notoginseng, Salvia miltiorrhiza, Rhodiola rosea, ginkgo leaves, Chuan Fritillaria, Anemarrhena, etc., add water to decoct Three times, filter, combine the filtrates, concentrate to a thick paste with a relative density of 1.30-1.35 (60°C), add Cordyceps mycelium, earthworm and leech fine powder, and add pharmaceutically acceptable auxiliary materials (such as appropriate amount of starch), Mix evenly, spray with 80% ethanol to granulate, dry, granulate, and tablet to make 1000 tablets, which is the comp...

Embodiment 2

[0102] prescription:

[0103] Cordyceps mycelium 42g Breviscapus 317g Notoginseng 317g Salvia 317g

[0104] Rhodiola 211g Ginkgo biloba 211g Chuan Fritillaria 127g Leeches 32g

[0105] Anemarrhena 127g Dilong 32g

[0106] Preparation method: the preparation of the composition is the same as in Example 1;

[0107] Capsules: add starch to the composition, mix evenly, spray with 80% ethanol to granulate, dry, add fillers such as magnesium stearate to granulate, pack into capsules, and obtain the capsules of the present invention.

[0108] The result shows: the composition capsule of the present invention meets relevant regulations under the capsule item.

Embodiment 3

[0110] Prescription: 1 part of Chuan Fritillaria, 0.1-1.0 parts of Cordyceps mycelium, 1.5-4 parts of Panax notoginseng, 1-3 parts of Rhodiola rosea, 1-5 parts of Erigeron breviscapita, 1-5 parts of Salvia miltiorrhiza, 1-3 parts of Ginkgo biloba parts, 0.1-0.6 parts of leech, 1-5 parts of Anemarrhena, and 0.1-0.6 parts of earthworm.

[0111] Preparation:

[0112] Take the above ten flavors, take Cordyceps mycelium, earthworm and leech, and crush them into fine powder, and set aside; take another seven flavors, such as erigeron breviscapita, Panax notoginseng, Salvia miltiorrhiza, Rhodiola rosea, ginkgo leaves, Chuan Fritillaria, Anemarrhena, etc., add water to decoct Three times, the weight of adding water is 1-26 times of the weight of the Chinese herbal medicine, respectively 10 times, 8 times, and 8 times, filtering, combining the filtrate, concentrating to a thick paste with a relative density of 1.30-1.35 (60°C), adding Cordyceps mycelium, earthworm and leech fine powde...

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Abstract

The invention relates to a Chinese medicinal composition for treating pulmonary interstitial fibrosis, which comprises the following Chinese medicinal components by weight portion: 1 portion of unibract fritillary bulb, 0.1 to 1.0 portion of Paecilomyces bepiali chen, 1.5 to 4 portions of pseudo-ginseng, 1 to 3 portions of Rhodiola rosea L., 1 to 5 portions of Breviscapinun, 1 to 5 portions of red sage root, 1 to 3 portions of ginkgo leaf, 0.1 to 0.6 portion of sanguisuga, 0.1 to 0.6 portion of earthworm and 1 to 5 portions of Common Anemarrhena Rhizome; and the Chinese medicinal components are raw powder of the Chinese medicinal materials or Chinese medicinal extracts equal to crude drug dosages of the Chinese medicinal materials. The Chinese medicinal composition can be used for treating diseases such as pulmonary interstitial fibrosis and the like.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, specifically, a traditional Chinese medicine composition for treating diseases such as pulmonary interstitial fibrosis. The components of the composition can be Chinese medicinal materials and / or Chinese medicine extract obtained by extraction. Background technique [0002] Idiopathic interstitial pulmonary fibrosis (abbreviated as IPF, pulmonary fibrosis) is characterized by progressive dyspnea, wheezing, shortness of breath, dry cough, wheezing, restrictive ventilation dysfunction, hypoxemia, chronic progressive Pulmonary interstitial disease characterized by diffuse pulmonary fibrosis. Early alveolitis eventually leads to irreversible fibrosis. The pathogenesis of idiopathic pulmonary interstitial fibrosis is complicated. Complex inflammatory pathogenic factors lead to immune regulation disorder, oxygen free radical damage, and imbalance of collagen metabolism, which lead to the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61P11/00A61K35/62A61K35/64
Inventor 杜树山姜良铎姚雪花沈圣民张海鸣史培军张文生张晓梅
Owner BEIJING NORMAL UNIVERSITY
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