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Drug for curing asthma

A technology for asthma and drugs, which is applied in the field of drugs for the treatment of asthma, and can solve problems such as side effects of the nervous system, peptic ulcers, and large side effects of hormones

Inactive Publication Date: 2009-10-07
辽宁省中医药研究院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the side effects of hormones are large. Long-term high-dose application may inhibit the function of the hypothalamus-pituitary-adrenal axis, which may lead to complications such as hypertension, steroid-induced diabetes, osteoporosis, and peptic ulcers, and may also cause drug dependence or drug resistance. , steroid-resistant asthma and steroid-dependent asthma
However, the therapeutic dose of theophylline is closer to the poisoning dose, and the safety range is narrower. Generally, a concentration higher than 20 μg / ml will cause side effects on the gastrointestinal tract, cardiovascular system and nervous system, and its application is also limited to a certain extent.
In addition, at this stage, immunotherapy and gene therapy are still in the scientific research stage, and it is difficult to apply them in a large scale and widely in clinical practice.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0080] Take 9g of raw materials, Sun-roasted Ephedra, 9g of Chuanshanlong, 9g of Dilong, 6g of Schisandra, and 9g of Licorice. Among them, Schisandra chinensis was crushed, extracted twice with 60% ethanol, 1.5 hours each time, filtered, and the dregs were kept for use, the filtrate was combined, ethanol was recovered, concentrated, and set aside; other ephedra, earthworm, panshania, licorice and Schisandra were extracted with alcohol After extracting the dregs, water was extracted 2 times, adding 7 times of water for the first time, and 6 times of water for the second time, each time for 1 hour, filtering, merging the filtrate, concentrating the filtrate to a relative density of 1.08, adding an alcohol content of up to Precipitate with 70% ethanol, filter, recover ethanol from the supernatant, combine with the above-mentioned schisandra alcohol solution, continue to concentrate to a clear paste with a relative density of 1.35, add sugar powder and dextrin to granulate, and the...

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Abstract

The invention relates to a drug for curing asthma, which is prepared by the following bulk drugs including 5-10g of Chinese ephedra, 5-15g of yam rhizome, 5-15g of earthworm, 5-9g of schisandra fruit and 5-15g of liquorice. The provided drug for curing asthma belongs to a traditional Chinese medicine preparation, and the pharmacological experiment and the clinical experiment show that the drug can treat both principal and secondary aspect of diseases, has the characteristics of fast effect, good therapeutic effect and no toxic side effect and is convenient for taking and carrying.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a medicine for treating asthma. Background technique [0002] Bronchial asthma (hereinafter referred to as asthma) is an allergic inflammatory disease characterized by airway hyperresponsiveness (AHR) involving various cells, cytokines and inflammatory mediators. Due to the intricate pathogenesis of asthma, it is still not fully understood. At present, western medicine studies on the pathogenesis of asthma mainly focus on the theory of airway inflammation, the theory of immunity and allergy, the mechanism of airway nerve regulation, and the genetic mechanism. Asthma can occur at any age, has an obvious family history, has the characteristics of recurrent attacks, and has a long course of disease. If it is not controlled in time, it may cause serious complications and even cause death. Moreover, its morbidity and mortality are increasing day by day. It is one of the ...

Claims

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Application Information

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IPC IPC(8): A61K36/57A61P11/06A61K35/36A61K35/64A61K35/62
Inventor 郭振武乔世举张宏王月敏于雪峰张雅凤甘雨朱希卓张颖李玉英周淑梅孟莉包玉龙王祺马进石绍顺焦岩赵秋阳于国强李明飞刘君
Owner 辽宁省中医药研究院
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