Production technique for extracting and separating isoflavone from red clover

Abstract

The invention relates to a production technique for extracting and separating isoflavone from red clover, comprising the following steps: the dry red clover raw material is crushed and extracted by high degree alcohol in a dynamic way; after being filtered, the extracted liquid medicine is decompressed and concentrated to have no alcohol smell and then extracted by the mixed solvent formed by moderate polar hydrophobic solvent A and weak polar solvent B until active ingredients are completely transfered into mixed solvent phase; the extracted mixed solvent phase is concentrated and recovered, and then added with the weak polar solvent B for crystallization; the precipitate which is separated is processed by vacuum drying, so that the isoflavone product can be obtained. Compared with the prior art, the yield of the isoflavone prepared by the method is improved by 20-30%, and the cost of the production can be reduced by 20-30%.

Description

technical field [0001] The invention relates to a production process for extracting and separating isoflavones from red clover. Background technique [0002] Red clover (Trifolium pratense L) is a leguminous plant, and its aerial part contains a variety of isoflavones, mainly formononetin, biochanin A, daidzein, Genistein, Sission, and Ononin all have estrogen-like effects. It has been clinically proven that they can prevent breast cancer, prostate cancer, and colon cancer, and improve osteoporosis and menopause symptom. It is a promising natural health food. [0003] There are two main production methods for extracting and separating isoflavones from the existing red clover: one is to obtain a product with an isoflavone content higher than 20% after alcohol extraction, concentration, water precipitation, degreasing, drying and refining, and the operation is cumbersome , the operation workload is large and the cost is high; the other is a product with an isoflavone conten...

AI Technical Summary

Problems solved by technology

[0003] There are two main production methods for extracting and separating isoflavones from the existing red clover: one is to obtain a product with an isoflavone content higher than 20% after alcohol extraction, concentration, water precipitation, degreasing, drying and refining, and the operation is cumbersome , the operation workload is large and the cost is high; the other is a product with an isoflavone content higher than 20% after alcohol extraction, which is concentrated, acid hydrolyzed, and refined. Due to the effect of acid, the color and smell of the product are different from natural extraction. Market acceptance is not high