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Application of Chinese medicinal composition in preparing medicament for treating chronic fatigue syndrome

A technology of chronic fatigue and composition, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of the application of chronic fatigue syndrome of undisclosed traditional Chinese medicine composition, etc.

Inactive Publication Date: 2009-12-23
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The above-mentioned patent does not disclose the application of the traditional Chinese medicine composition in the treatment of chronic fatigue syndrome

Method used

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  • Application of Chinese medicinal composition in preparing medicament for treating chronic fatigue syndrome
  • Application of Chinese medicinal composition in preparing medicament for treating chronic fatigue syndrome
  • Application of Chinese medicinal composition in preparing medicament for treating chronic fatigue syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The raw material drug formula is:

[0034] Jujube 30g, mulberry 30g, ganoderma lucidum 10g, lily 5g

[0035] Hawthorn 10g, Poria 5g, tangerine peel 5g, chrysanthemum 10g, lotus leaf 5g;

[0036] Preparation:

[0037] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0038] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C and heat the clear paste with a relative density of 1.20-1.25, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, and reduce the pressure Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and se...

Embodiment 2

[0041] The raw material drug formula is:

[0042] Jujube 36g, Mulberry 36g, Ganoderma lucidum 10g, Lily 6g

[0043] Hawthorn 12g, Poria cocos 6g, tangerine peel 6g, chrysanthemum 12g, lotus leaf 6g

[0044] Preparation:

[0045] (1) Take Chinese medicinal materials according to the prescription amount, and select them;

[0046] (2) Mix the above net-selected medicinal materials, make coarse powder, add 9 times the amount of water, soak for 1 hour, heat and decoct 2 times, the first time is 1.5 hours, the second time is 1 hour, filter, combine the filtrate, reduce Concentrate under pressure to 60°C and heat the clear paste with a relative density of 1.20-1.25, add 95% ethanol to adjust the concentration to 75%, let it stand below 4°C for 24 hours, filter, and recover the ethanol from the filtrate under reduced pressure until it has no alcohol smell, and reduce the pressure Concentrate to a liquid extract with a relative density of 1.02-1.06 when thermally measured at 60°C, and...

Embodiment 3

[0049] In order to illustrate the activity of Chinese medicine composition of the present invention in treating chronic fatigue syndrome, the following animal experiments have been carried out with the oral liquid (hereinafter referred to as the present invention's medicine) that is made by the method of embodiment 1.

[0050] 1. Materials and methods

[0051] 1.1 Main Drugs and Reagents

[0052] Drugs of the present invention (provided by Hebei Yiling Medical Research Institute Co., Ltd.); SOD, MDA, NO kits (provided by Nanjing Jiancheng Biological Reagent Company); ET, Ang II radioimmunoassay kits (provided by East Asia Radioimmunotherapy Institute, General Hospital of the Chinese People's Liberation Army).

[0053] 1.2 Methods Grouping and administration of animals:

[0054] METHODS: The "forced weight-bearing swimming" method was used to establish a model of rat exercise fatigue, and the activity of superoxide dismutase (SOD), malondialdehyde (MDA), nitric oxide (NO) in s...

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Abstract

The invention discloses application of a Chinese medicinal composition in preparing a medicament for treating chronic fatigue syndrome. The Chinese medicinal composition consists of nine Chinese medicaments such as wild jujube, mulberry and the like, has the efficacies in nourishing Yin, calming the nerves, and harmonizing Qi and blood, and simultaneously can treat sub-health and exercise fatigue caused by overstrain belonging to the chronic fatigue syndrome.

Description

technical field [0001] The invention relates to a new application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for treating chronic fatigue syndrome, which belongs to the field of traditional Chinese medicine applications. Background technique [0002] Chronic fatigue syndrome is a common disease in persistent sub-health state. The disease is most likely to occur in middle age, and the symptoms are various, such as fatigue that is not easy to relieve due to physical or psychological overload; muscle weakness without a clear cause; insomnia, dreaminess and early awakening; Headache; difficulty concentrating, memory loss; loss of appetite; shoulder and back discomfort, chest tightness, or low back pain, non-localized muscle pain and joint pain; depression, anxiety or nervousness, fear; loss or loss of interest ; Sexual power decline, etc. The disease has an incide...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/896A61K9/10A61K9/20A61K9/48A61P43/00
Inventor 李向军安军永王超郑立发
Owner HEBEI YILING MEDICINE INST