Method for plastically manufacturing high-purity magnesium alloy absorbable stent

A vascular stent and plastic processing technology, which is applied in the direction of stents, manufacturing tools, and other manufacturing equipment/tools, can solve the problems of poor corrosion resistance, low yield strength, and easy damage to cells, so as to improve yield strength and plasticity, improve Yield strength, the effect of eliminating hardening of blood vessels

Inactive Publication Date: 2010-03-03
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0023] The purpose of the present invention is to solve the problems of low yield strength, poor plasticity, poor corrosion resistance and easily damaged

Method used

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Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0034] Embodiment 1: The steps of the plastic processing and manufacturing method of the high-purity magnesium alloy absorbable vascular stent of the present embodiment are as follows:

[0035] Step 1: preparing a Mg-Al-Zn or Mg-Zn-Ca alloy ingot with a purity greater than 99.99%, wherein the mass percentage of Al in the composition of the Mg-Al-Zn alloy ingot with a purity greater than 99.99% is 2.6-3.0 %, the mass percentage of Zn is 0.6-1.0%, the main impurities are Mn, Fe, Si, Cu and Ni, the mass percentage of impurities is 0.005%, and the rest is Mg; the Mg-Zn-Ca alloy ingot with a purity greater than 99.99% The mass percentage of Zn in the composition is 4-5%, the mass percentage of Ca is 1-1.5%, the mass percentage of impurities is 0.005%, and the rest is Mg;

[0036] Step 2: Put the Mg-Al-Zn or Mg-Zn-Ca alloy ingot into the extruder for hot extrusion, the extrusion temperature is 300°C-400°C, the extrusion ratio is 6-10, and the extrusion speed is 20~30mm / s;

[0037] S...

specific Embodiment approach 2

[0043] Embodiment 2: This embodiment differs from Embodiment 1 in that the extrusion temperature in step 2 is 300° C., the extrusion ratio is 6.25, and the extrusion speed is 20 mm / s. The grains of the alloy billet after extrusion can be refined to less than 10 μm, and other steps and parameters are the same as those in the first embodiment.

specific Embodiment approach 3

[0044] Embodiment 3: This embodiment differs from Embodiment 1 in that the extrusion temperature in step 3 is 150° C., the extrusion ratio is 7.25, and the extrusion speed is 17 mm / s. The grains of the alloy billet after extrusion can be refined to less than 5 μm. Other steps and parameters are the same as those in Embodiment 1.

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PUM

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Abstract

The invention provides a method for plastically manufacturing a high-purity magnesium alloy absorbable stent, relating to a metal stent manufacturing method for the field of intravascular interventional treatment. The method solves the problem of angiosclerosis caused by low yield strength, poor plasticity, poor corrosion resistance and easy damaged cells existing in the prior absorbable stent. The method comprises the following steps: preparing a high-purity Mg-Al-Zn or Mg-Zn-Ca alloy ingot; refining crystalline grains through heat extruding, warm extruding and cold extruding; machining an alloy blank which is extruded for three times into a tube blank; processing the tube blank by multi-pass cold drawing process on the tube blank; machining the thin walled tube into a stent; putting thestent into fluid polishing solution for fluid polishing and burr removing. The method greatly improves the corrosion resistance, yield strength and plasticity, meets the clinical requirement on resorbing speed and time of the intravascular stent, and eliminates the problem of angiosclerosis; and the compositions of the high-purity magnesium alloy stent have higher safety and reliability.

Description

technical field [0001] The invention relates to a processing and manufacturing method of a metal stent used in the field of intravascular interventional therapy, in particular to a plastic processing and manufacturing method of a high-purity magnesium alloy absorbable vascular stent. Background technique [0002] Interventional therapy has become an important branch of the medical field. The research on the interaction between interventional materials and human tissues has attracted more and more attention. The so-called human tissues refer to blood vessels, bones, organs and body fluids. Especially the emergence of biomaterials makes this field the most promising direction. However, metallic materials play an important role in interventional medicine. [0003] At present, vascular stents are mainly made of stainless steel or cobalt-chromium-nickel alloy. However, these materials have great side effects on blood vessels, which can easily cause hardening of blood vessels an...

Claims

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Application Information

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IPC IPC(8): A61L27/04A61L27/58A61F2/82B23P23/04
Inventor 王欣王尔德杨成远杨德山
Owner HARBIN INST OF TECH
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