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Pharmaceutical composition for preventing and treating warm-heat diseases of livestock and poultry and preparation method thereof

A technology for febrile disease and composition, which is applied in the field of febrile disease pharmaceutical composition and preparation thereof, can solve the problems of single function, difficult compound ingredients and the like, and achieves the effects of simple operation and convenient use

Active Publication Date: 2010-05-05
LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the complexity of the mechanism of action of traditional Chinese medicine in animals and the difficulty in quantifying the components of the compound formula, it is still very difficult to develop and screen a very effective drug that can be applied on a large scale in clinical practice and has high technical added value. Traditional Chinese and Western medicines are still the mainstay, and the function is single

Method used

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  • Pharmaceutical composition for preventing and treating warm-heat diseases of livestock and poultry and preparation method thereof
  • Pharmaceutical composition for preventing and treating warm-heat diseases of livestock and poultry and preparation method thereof
  • Pharmaceutical composition for preventing and treating warm-heat diseases of livestock and poultry and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] ①Weigh 400g forsythia, 200g isatidis root, 200g honeysuckle, 200g scutellaria, 200g coptis, 200g comphelia, 100g licorice into the tank, add 10 times the amount of medicine for the first time, soak in distilled water for 15 minutes, heat to boiling, and keep boiling 1.5 hours; filter to take the filtrate; add 8 times the amount of water to the filter residue, heat to boiling and extract for 1 hour, filter and collect the filtrate; combine the two filtrates, heat and concentrate to 5000ml;

[0032] ② Cool the concentrated filtrate obtained in ① to below 40°C, add 95% ethanol to make the ethanol concentration of the medicinal solution 75%, let it rest for 16 hours, and filter with suction, and recover the ethanol from the filtrate until it has no alcohol smell. Then add 95% ethanol to make the alcohol content in the solution 80%, stand still for 16 hours, filter with suction, recover ethanol from the filtrate and concentrate to obtain a thick liquid. Add water for injecti...

Embodiment 2

[0035] ①Water extraction Weigh 400g Forsythia, 200g Banlangen, 200g Honeysuckle, 200g Scutellaria, 200g Coptidis, 200g Coptymia, 100g Licorice into the tank, add 7 times the amount of medicine for the first time to soak in distilled water for a while, heat to boiling, keep Boil for 1.5 hours; filter to take the filtrate; add 6 times the amount of water to the filter residue, heat to boiling and extract for 1 hour, filter and collect the filtrate; combine the two filtrates, heat and concentrate to 4000ml;

[0036] ②Alcohol precipitation and cooling to below 40°C, adding 95% ethanol to make the ethanol concentration of the medicinal liquid 75%, resting for 24 hours, suction filtration, recovering ethanol from the filtrate until it has no alcohol smell. Then add 95% ethanol to make the alcohol content in the solution 80%, stand still for 24 hours, filter with suction, recover ethanol from the filtrate and concentrate to obtain a thick liquid. Add water for injection to 1300ml, ad...

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Abstract

The invention discloses a pharmaceutical composition for preventing and treating warm-heat diseases of livestock and poultry and a preparation method thereof. The mix proportion by weight of a variety of traditional Chinese medicines calculated by raw plant drugs and dressings in 1500ml of liquid medicine is as follows: 350-450g of fructus forsythiae, 150-250g of indigowoad root, 150-250g of honeysuckle flower, 150-250g of baical skullcap root, 150-250g of golden thread, 150-250g of commelina communis, 75-125g of liquoric root, 2-3g of benzyl alcohol and the balance of distilled water. The preparation method of the pharmaceutical composition comprises three steps of water extraction, ethanol precipitation and preparation of the liquid medicine, thereby preparing an injection. A large number of clinical uses prove that the medicine has the effects of anti-virus, anti-bacteria, anti-inflammation, clearing heat-toxin and enhancing immunity and excellent treatment effect on warm diseases which are mainly characterized by fever, and the applications thereof can play the positive role of promoting the development of the livestock and poultry industry in China.

Description

technical field [0001] The invention belongs to a febrile disease medicinal composition mainly characterized in preventing and treating fever of livestock and poultry and a preparation method thereof. Background technique [0002] With the rapid development of my country's intensive breeding industry and the continuous improvement of feeding and management levels, the incidence of various common diseases of livestock and poultry has decreased, while febrile diseases characterized by fever (including various acute infections in Western veterinary medicine) diseases and infectious diseases) the incidence rate is on the rise, such as swine flu, blue ear disease, porcine streptococcal disease, avian influenza, mad cow disease, foot-and-mouth disease, schistosomiasis and other diseases seriously damage the healthy development of animal husbandry and aquaculture. It has caused serious economic losses, and at the same time, it has also caused great threats to human health and public ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P29/00A61P31/04A61P31/14A61P31/16A61P37/04
Inventor 李剑勇张继瑜李新圃杨亚军周绪正牛建荣魏小娟李冰陈佳娟
Owner LANZHOU INST OF ANIMAL SCI & VETERINARY PHARMA OF CAAS
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