Medicinal composition for expelling phlegm and inhibiting cough and preparation method thereof

A technology for eliminating phlegm and relieving cough and composition, which is applied in the field of pharmaceutical composition and its preparation, and can solve problems such as inappropriate long-term use of antibiotics

Active Publication Date: 2010-05-19
广西厚德药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine uses codeine, ammonium chloride and other antitussive and phlegm-resolving drugs for symptomatic treatment of symptoms such as phlegm and cough. Although the symptoms can be temporarily controlled, antibiotics and other antibacterial drugs must be used in combination to achieve the purpose of cure. Cause more serious consequences and drug resistance, some coughs caused by chronic bronchitis should not be treated with antibiotics for a long time

Method used

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  • Medicinal composition for expelling phlegm and inhibiting cough and preparation method thereof
  • Medicinal composition for expelling phlegm and inhibiting cough and preparation method thereof
  • Medicinal composition for expelling phlegm and inhibiting cough and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0105] Mangosteen 400g, pine cone 380g, mango leaves 400g, sweet tea 220g, ephedra 220g

[0106] The above raw materials are decocted three times with water, adding 6 times of water each time, decocting for 2 hours each time, filtering the decoction, concentrating the filtrate to a relative density of 1.25 at 60°C, adding ethanol to make the alcohol content reach 85%, stirring well, Stand still for 24 hours, filter, recover ethanol from the filtrate, concentrate to an extract with a relative density of 1.30 at 60°C, dry, pulverize, add microcrystalline cellulose, granulate, dry, add magnesium stearate, mix well, and press into tablets.

Embodiment 2

[0108] Luo Han Guo 330g Pine Cone 300g Mango Leaf 330g Sweet Tea 180g Ephedra 180g

[0109] The above raw materials were decocted three times with water, followed by adding 10 times, 8 times, and 8 times of water, the first 1.5 hours, the second 1 hour, and the third 1 hour, filtered, combined the filtrate, concentrated to 6 liters, added 5 liters of 0.1% chitosan-1% citric acid solution, stir well, let stand for 24 hours, filter the supernatant, concentrate to extract with relative density of 1.20 (60°C), add 450g of sucrose and 3g of sodium benzoate , boil to dissolve, add water to 1000ml, stir well, filter to obtain syrup.

Embodiment 3

[0111] Mangosteen 350g, pine cone 320g, mango leaves 330g, sweet tea 150g, ephedra 180g

[0112] Add water to decoct the above materials twice, add 15 times the amount of water for the first time, decoct for 0.5 hours, add 13 times the amount of water for the second time, decoct for 1 hour, filter the decoction, and concentrate the filtrate to a relative density of 1.10 at 60°C The medicinal extract is dried, pulverized, added with starch, magnesium stearate, talcum powder, mixed evenly, filled into hollow capsules, and made into capsules.

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PUM

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Abstract

The invention discloses a medicinal composition. The medicinal composition mainly comprises momordica grosvenori, pinecone, hydrangea aspera don, mango leaves and ephedra. The medicinal composition has an obvious effect of expelling phlegm and inhibiting cough, and can be prepared into various oral preparations which are beneficial to administration of patients.

Description

field of invention [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition with functions of eliminating phlegm and relieving cough and a preparation method thereof. Background technique [0002] Respiratory system disease is a common and frequently-occurring disease. After the onset, the common clinical symptoms are phlegm, cough, wheezing, shortness of breath, itchy or sore throat, wheezing, nasal congestion, runny nose, etc. It can be caused by cold, acute and chronic bronchial Diseases such as inflammation cause, no matter men, women, old or young, all can fall ill all the year round, and patient is numerous, and this disease affects patient's work, rest, has a strong impact on patient's health. At present, although there are many drugs for the clinical treatment of such diseases, the curative effect is not satisfactory. Western medicine uses codeine, ammonium chloride and other antitus...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/42A61P11/10A61P11/14
Inventor 唐弟光莫少红梁霞阮碧芳梁尚焕韦慧鲜李品蒙华英
Owner 广西厚德药业有限公司
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