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Artemisia dalai-lamae Krasch. essential oil and preparation method and application thereof

A technology of volatile oil and Artemisia annua, applied in pharmaceutical formulations, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of large treatment limitations, high disability rate, helplessness, etc., and achieve simple process flow and equipment investment. The effect of small size and low production cost

Inactive Publication Date: 2010-06-02
CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Surgical treatment has great limitations, and the treatment rate for patients with tumor cell spread is low or even helpless. Even if surgery is performed, the disability rate is also high
The goal of chemotherapy drugs is to inhibit the proliferation of cancer cells. The commonly used chemically synthesized anti-tumor drugs are not specific. While killing tumor cells, they also have certain effects on proliferating normal cells, leading to vomiting, diarrhea, hair loss, and bone marrow suppression. and other adverse reactions, causing pain to patients and affecting the quality of life of patients

Method used

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  • Artemisia dalai-lamae Krasch. essential oil and preparation method and application thereof
  • Artemisia dalai-lamae Krasch. essential oil and preparation method and application thereof
  • Artemisia dalai-lamae Krasch. essential oil and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0042] Embodiment 1 A kind of preparation method of Artemisia sativa volatile oil, comprises the following steps:

[0043] (1) Remove impurities from 500g fresh twigs or fresh leaves of the above-ground part of Artemisia oryzae, cut them into sections of 0.5-3cm, put them into the volatile oil extractor produced by Shanghai Tongxin Biomedical Technology Co., Ltd., and use 4 times its weight Soak in water for 5 hours to fully infiltrate the broken pieces of Artemisia mirabilis.

[0044] (2) Move the volatile oil extractor containing Artemisia annua fragments and its soaking solution in step (1) to the 98-1-B electronic constant temperature electric heating mantle produced by Tianjin Test Instrument Co., Ltd. to carry out steam distillation , the distillation temperature was 80°C, the distillation time was 2h, and the distillate was collected.

[0045] (3) Natural cooling of the distillate, natural layering, discarding the water layer, taking the oil layer, drying with anhydrou...

Embodiment 2

[0046] Embodiment 2 A kind of preparation method of Artemisia sativa volatile oil, comprises the following steps:

[0047] (1) Remove impurities from 1 kg of fresh twigs or fresh leaves of the above-ground part of Artemisia japonica, cut them into sections of 0.5-3 cm, put them into a volatile oil extractor, soak them in water 10 times their weight for 2 hours, and make Artemisia japonica into pieces Fully infiltrate.

[0048] (2) Move the volatile oil extractor containing Artemisia annua fragments and its soaking solution in step (1) to the 98-1-B type electronic constant temperature electric heating mantle to carry out steam distillation, the distillation temperature is 120 ℃, and the distillation time is 6h, collect the distillate.

[0049] (3) Natural cooling of the distillate, natural layering, discarding the water layer, taking the oil layer, drying with anhydrous sodium sulfate in a weight ratio of 1:8, filtering out the solids to obtain the volatile oil of Artemisia m...

Embodiment 3

[0050] Embodiment 3 A kind of preparation method of Artemisia sativa volatile oil, comprises the following steps:

[0051] (1) Remove impurities from 2 kg of fresh twigs or fresh leaves of the above-ground part of Artemisia japonica, cut them into sections of 0.5-3 cm, put them in a volatile oil extractor, soak them in water 7 times their weight for 4 hours, and make Artemisia japonica into pieces Fully infiltrate.

[0052] (2) Move the volatile oil extractor containing Artemisia annua fragments and its soaking solution in step (1) to the 98-1-B type electronic constant temperature electric heating mantle to carry out steam distillation, the distillation temperature is 100 ℃, and the distillation time is 4h, collect the distillate.

[0053] (3) Natural cooling of the distillate, natural layering, discarding the water layer, taking the oil layer, drying with anhydrous sodium sulfate in a weight ratio of 1:5, and filtering out the solids to obtain the volatile oil of Artemisia ...

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Abstract

The invention relates to Artemisia dalai-lamae Krasch. essential oil which is light yellow transparent liquid with heavy fragrance and is freely soluble in alcohols and liposoluble solvents. The essential oil comprises the following main chemical components: alcohol, alkane, alkene and ketone compounds and mainly comprises 20-30% of myrtenol, 5-15% of eucalyptol, 5-15% of 1,3-dimethyl-5-ethylbenzene, 5-15% of myrcene, 3-9% of (Z)-3,7-dimethyl-octatriene (1,5,7) alcohol-3, 3-9% of adamantine, 3-9% of 3,3,6-trimethyl-heptadiene (1,4) alcohol-6, 2-6% of 3,3,6-trimethyl-heptadiene (1,5) alcohol-4, 2-6% of 4-methyl-heptadiene (1,6) alcohol-4 and 2-6% of alpha-pinene by mass. Meanwhile, the invention also discloses a preparation method of the essential oil, which is characterized by high extraction ratio and simple process flow. With antibacterial, antineoplastic, expectorant and antitussive active components, the Artemisia dalai-lamae Krasch. essential oil can be applied to treating respiratory disorders.

Description

technical field [0001] The invention relates to a plant volatile oil, in particular to the volatile oil of Artemisia oryzae, as well as its preparation method and application. Background technique [0002] With the improvement of human living standards, the extensive application of antibiotics and chemical drugs has caused some fungi to develop drug resistance, which poses a serious threat to human production and life. Medical experts from all over the world are constantly working on finding preventive agents with less toxic and side effects and less fungal resistance. my country's Chinese herbal medicine is rich in resources, highly effective, low in toxicity, and low in cost. The vast number of Chinese medicine workers have made a lot of beneficial attempts on the antibacterial and antibacterial activities of Chinese herbal medicines, and accumulated a lot of experience. [0003] Tumors are a common condition. According to statistics, there are more than 10 million new ...

Claims

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Application Information

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IPC IPC(8): A61K36/28A61P11/00A61P31/04A61P35/00A61K127/00A61K131/00
Inventor 罗智敏陶燕铎邵赟张兴旺梅丽娟
Owner CHINA ACAD OF SCI NORTHWEST HIGHLAND BIOLOGY INST
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