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Method for preparing gallic acid aquiculture sanitizer and product thereof

A gallic acid, disinfection and sterilization technology, applied in the direction of disinfectants, fungicides, botanical equipment and methods, etc., can solve the problems of difficult control of drug solubility and product quality, low bioavailability, unstable control effect, etc., to achieve Product quality is stable and controllable

Active Publication Date: 2013-04-03
JIURUI BIOLOGY & CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These Chinese herbal medicines and aquatic fish medicines are all directly used with raw medicinal materials such as Galla chinensis. The processed dosage form is backward, the drug onset is slow, the bioavailability is low, the drug solubility and product quality are difficult to control, and the control effect is unstable.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Embodiment 1: preparation of gallic acid aqueous solution

[0018] Gallnut 200g, crushed, passed through a 40-mesh sieve, put into a microwave extraction tank with a power of 1200W, a volume of 5L, added 2000ml of pure water and 22ml of liquid caustic soda, stirred and extracted, microwave frequency 2450MHz, microwave extraction time 30min. After extraction, coarse filtration, fine filtration, ultrafiltration with a 50,000 molecular weight polysulfone membrane, and nanofiltration of the ultrafiltered dialyzate with a 500 molecular weight polysulfone membrane; the nanofiltration retentate was bottled with an emulsifier to obtain 752ml of gallic acid water, gallic acid Acid content 12.5%.

Embodiment 2

[0019] Embodiment 2: preparation of gallic acid powder

[0020] Gallnut 200g, crushed, passed through 40 mesh sieve, input power 1200W, volume 5L microwave extraction tank, add 2000ml pure water, 22ml liquid caustic soda, stir extraction, microwave frequency 2450MHz, microwave extraction time 60min. After extraction, coarse filtration, fine filtration, ultrafiltration with a 50,000 molecular weight polysulfone membrane, and nanofiltration of the ultrafiltered dialyzate with a 500 molecular weight polysulfone membrane; the nanofiltration retentate was concentrated and spray-dried to obtain 95.6 g of gallic acid powder, gallic acid The content is 83.6%.

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PUM

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Abstract

The invention provides a method for preparing gallic acid aquiculture sanitizers and products thereof, which comprises the following steps: filtrating gallnut by microwave centrifugation; micro-filtrating; fine-filtrating; ultra-filtrating the fine-filtrated liquid with polysulphone membrane of 50,000 molecular weight, and recycling the trapped fluid by ultra-filtration for extraction; and nano-filtrating the ultra-filtrated dialysate, and recycling the nano-filtrated dialysate for extraction, thus obtaining the products. The products can be made into aqua and powder. The products of the invention have good control effect on various diseases, such as gill-rot disease, white skin disease, red skin disease, scabies disease, fungous saprolegniasis, branchiomycosis and the like, from aquatic animals, such as fish, shrimp, crab, turtle, and frog, etc. Besides, the products do not cause water environmental pollution due to little residue in the aquatic products, so that quality of the products is stable and controllable.

Description

technical field [0001] The invention relates to the preparation of a high-efficiency and low-toxicity disinfectant for aquatic products, in particular to a method for preparing the disinfectant for aquatic products with natural medicine gallic acid and the product thereof. Background technique [0002] my country is a big aquaculture country in the world, and its output accounts for about 80% of the world's aquaculture output. With the continuous expansion of the scale of aquaculture and the continuous improvement of the degree of intensification, coupled with the deterioration of the aquaculture environment, the incidence of aquaculture diseases is increasing, and the pathogens are mainly bacterial diseases. In 2003, 144 species were monitored nationwide. Diseases, including 60 kinds of bacterial diseases, accounting for 41.7%, followed by 39 kinds of parasitic diseases. The direct economic losses caused by breeding diseases in that year amounted to 10.584 billion yuan. I...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01N37/40A01N25/12A01N25/02A01P1/00A01P3/00
Inventor 王文茂汤先赤陈学勇汤赫
Owner JIURUI BIOLOGY & CHEM CO LTD
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