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Method for extracting medicament for treating allergic colitis from Alhagi sparsifolia plant and medicament and application thereof

A camel thorn and allergic technology, which is applied in the field of traditional Chinese medicine preparations for the treatment of allergic colitis, can solve the problems of low content of active substances, low production rate of thorn sugar, and affecting application effects, etc., achieves small toxic and side effects, and improves immunity. Ability, efficacy, long-lasting effect

Inactive Publication Date: 2014-12-31
新疆维吾尔自治区中药民族药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the low output rate of thorn sugar, it is not easy to collect, the content of effective substances is low, and it also contains some unknown substances that may have toxic and side effects on the human body, thus affecting its application effect.

Method used

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  • Method for extracting medicament for treating allergic colitis from Alhagi sparsifolia plant and medicament and application thereof
  • Method for extracting medicament for treating allergic colitis from Alhagi sparsifolia plant and medicament and application thereof
  • Method for extracting medicament for treating allergic colitis from Alhagi sparsifolia plant and medicament and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Reflux extraction: Take the dried and crushed aerial part of camel thorn, dry it until the moisture content is ≤15%, and crush it into segments or granules below 3mm; place it in 25000-40000ml of 60-95% ethanol for 2 hours and repeat for every 10kg Carry out 3 times, the amount of ethanol used for the first time is 40000ml, and the amount of ethanol for the next two times is 30000ml.

[0031] Concentration: Combine the above extracts and concentrate in a rotary evaporator until the dry matter content is 20-40% to obtain an extract;

[0032] Extraction: a. Extract with ethyl acetate that is 3 times the volume of the concentrated extract, stir well and let it stand for 4 to 6 hours to clarify until obvious layers appear, remove the ethyl acetate layer and retain the water-soluble layer; b. Use step a Extract with n-butanol in an amount 3 times the volume of the water-soluble layer, fully stir and let it stand for 4 to 6 hours to clarify until obvious stratification occurs...

Embodiment 2

[0034] Compared with Example 1, the difference of this example is that: before the extraction step a, extract with 60-90°C petroleum ether in an amount 3 times the volume of the extract, fully stir and let it stand for 4-6 hours to clarify until obvious separation occurs. layer, take the water-soluble layer; the obtained water-soluble layer is extracted with chloroform in an amount 3 times the volume, fully stirred and left to stand for 4 to 6 hours to clarify until obvious layers appear, and the water-soluble layer is taken to enter the extraction step a.

Embodiment 3

[0036] Compared with Example 1, the difference of this example is that the extraction is as follows: a. Extract with ethyl acetate in an amount 3 times the volume of the concentrated extract, fully stir and let it stand for 4 to 6 hours to clarify until obvious Separate the layers, remove the ethyl acetate layer and retain the water-soluble layer, and repeat the extraction of the water-soluble layer with 2 times the amount of ethyl acetate for 2 times, b. Extract with n-butanol of 3 times the volume of the water-soluble layer in step a, and let it stand Clarify for 4 to 6 hours until there are obvious layers, take the n-butanol layer, and repeat the extraction of the water-soluble layer with 2 times the amount of n-butanol for 2 times, and combine the 3-time n-butanol layer solution in a rotary evaporator Concentrate to a dry matter content ≥ 75%, and the obtained extract is the medicine of the present invention.

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Abstract

The invention discloses a method for extracting a medicament for treating allergic colitis from an Alhagi sparsifolia plant and the medicament and application thereof. The medicament is prepared by the steps of reflux extraction, concentration, extraction, concentration, and the like and can be used for treating diseases, such as allergic colitis, and the like. The medicament of the invention is a pure Chinese herbal medicine preparation; and tests prove that the medicament can improve the immune system of an animal body and immune ability, especially has more obvious effect on the allergic colitis disease, has the characteristics of lasting curative effect and small toxic and side effects, and can be widely applied to various medicaments for treating the allergic colitis disease.

Description

Technical field: [0001] The present invention relates to a traditional Chinese medicine preparation for treating allergic colitis with anti-allergic effects, a production method thereof and the application of the traditional Chinese medicine preparation, in particular to a traditional Chinese medicine preparation for treating allergic colitis extracted from camel thorn plant and its preparation Production method and application of the traditional Chinese medicine preparation. Background technique: [0002] With the development of society, the environment of people's daily life presents more and more complex changes. Due to the influence of environmental factors in daily life, there are more and more allergic diseases. At present, anti-allergic drugs are mainly chemical drugs, and many It will have some side effects on the human body, especially for some diseases such as allergic colitis, and excessive use of chemicals will also cause irritation to the stomach. The use of Ch...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61P1/00A61P31/04A61P37/08
CPCY02A50/30
Inventor 熊元君贾晓光夏提古丽
Owner 新疆维吾尔自治区中药民族药研究所
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