Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Chinese medicament kudzu-vine root for preventing and treating vascular restenosis

A technology of restenosis and traditional Chinese medicine, which is applied in the field of Pueraria lobata, a traditional Chinese medicine, can solve the problems of finding no treatment method, failing to achieve the expected effect, and unsatisfactory prevention and treatment effect of blood vessel restenosis, so as to improve self-coordination ability, have no toxic side effects, improve The effect of clinical subjective symptoms

Inactive Publication Date: 2010-10-27
TAIYI HEPU BEIJING RES INST OF TCM
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the clinical effect of prevention and treatment of vascular restenosis is not ideal, the reason is that the formation of restenosis is a complex process involving multiple factors and multiple factors.
Modern medicine often fails to achieve the expected effect and cannot find a suitable treatment method for a certain clinical symptom. In order to overcome the above defects, the present invention is based on the principle of combining disease differentiation and syndrome differentiation in the prevention and treatment of vascular restenosis in traditional Chinese medicine. Treat both deficiency and excess, regulate both internal and external, and take both emergency and emergency. On the basis of summarizing clinical experience, natural plant medicine Pueraria lobata root and Pueraria lobata root Chinese medicine extract were screened out, and their mechanism of action was studied in depth.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0046] [Experimental example] The clinical efficacy observation experiment of the Chinese medicine composition of the present invention for patients with vascular restenosis

[0047] 1. Used for coronary heart disease and angina pectoris

[0048] He Fengyi et al. divided 66 patients with coronary heart disease and angina pectoris into two groups. 36 patients in the treatment group (26 males, 10 females, age 59+9 years old) were injected intravenously with 500mg of puerarin and 500ml of 10% glucose injection. 1 time / d, continuous use for 10 days; 30 cases in the control group (21 males, 9 females, age 58+8 years old) added potassium chloride and energy mixture to glucose injection, intravenous drip, 1 time / d, continuous use 10d. Results: The total clinical effective rate of the treatment group was 92%, the total effective rate of ECG was 69%, and the control group was 70% and 43%, suggesting that it can better improve the clinical symptoms of patients with coronary heart disease an...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a Chinese medicament kudzu-vine root for preventing and treating vascular restenosis, or a medicament composite comprising a kudzu-vine root which serves as a raw material, or the application of extractive which takes the kudzu-vine root as the raw material and serves as an active ingredient in the preparation of a medicament which is used for preventing and treating the vascular restenosis. The invention also discloses a method for preparing the medicament for preventing and treating the vascular restenosis. The Chinese medicament kudzu-vine root for preventing and treating the vascular restenosis is novel medicament application besides the original published medicament effect of the kudzu-vine root. The Chinese medicament kudzu-vine root for preventing and treating the vascular restenosis can obviously improve coronary heart diseases, apoplexy and sequel caused by atherosclerosis, and lumen restenosis caused by newly born endangium after angioplasty and artery scaffold treatment, regulate structural disorder caused by vascular remodeling, and effectively control thrombosis on an injured part and followed thrombus organization. The Chinese medicament kudzu-vine root for preventing and treating the vascular restenosis has the advantages of positive clinical effects, obvious curative effect and quick response, and compared with a scaffold operation and a bypass operation, the Chinese medicament kudzu-vine root also has the advantages of higher safety, lower cost, and more stable and more reliable late result.

Description

Technical field [0001] The invention relates to a traditional Chinese medicine Pueraria lobata root for preventing and treating vascular restenosis. In particular, it relates to a traditional Chinese medicine for preventing and treating vascular restenosis using the Chinese herbal medicine Pueraria lobata root as a raw material and a preparation method thereof. Background technique [0002] Atherosclerosis, coronary heart disease and stroke caused by it are the main diseases that endanger human health. Angioplasty is one of the main treatments for atherosclerosis. However, the neovascular intima after arterial balloon injury leads to lumen restenosis, which is the main reason for the failure of angioplasty and arterial stent treatment. Restenosis after percutaneous transluminal coronary angioplasty is mainly caused by the following three reasons: excessive proliferation of smooth muscle cells caused by injury; structural disorder caused by vascular remodeling; thrombosis at the...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/488A61K36/9066A61P9/00A61K35/56A61K35/586
Inventor 王峰王文奎
Owner TAIYI HEPU BEIJING RES INST OF TCM
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products