Inflammation and heat clearing tablets and preparation method thereof

Abstract

The invention discloses inflammation and heat clearing tablets. 1,000 inflammation and heat clearing tablets are prepared from raw materials of 160 to 180g of inflammation and heat clearing extract powder, 150 to 170g of filler, 13 to 15g of disintegrating agent, 0.8 to 2.0g of lubricating agent, 10 to 20g of silicon dioxide, 1.5 to 3.5g of menthol, 136 to 138g of baical skullcap root, a proper amount of povidone and a proper amount of ethanol by wet-process granulation and tabletting, wherein the inflammation and heat clearing extract powder is prepared by spray drying of inflammation and heat clearing extract. The invention also discloses a method for preparing the inflammation and heat clearing tablets. The tablets prepared by dissolving the menthol and the proper amount of ethanol, adding the silicon dioxide, mixing with the dry extract powder and tabletting have the stability effectively improved, and solve the problems of unqualified menthol identification, non-uniform content and unqualified hardness so as to improve product quality; and the method has the advantages of simple process flow, energy conservation, cost conservation and suitability for industrial production.

Description

technical field [0001] The invention relates to a Chinese patent medicine tablet and the field of preparation thereof, in particular to a Yanreqing tablet and a preparation method thereof. Background technique [0002] Yanreqing Tablets is made from Yanreqing Capsules that have been sold in the domestic market. It belongs to the 9th category of traditional Chinese medicine registration. It can be used for urinary system infection and biliary tract infection; the drug has good effect, is convenient to take, has few side effects, and is low in price. [0003] The existing prescription of Yanreqing Tablets is exactly the same as that of Yanreqing Capsules, generally according to the prescription of Yanreqing Capsules recorded in volume 8 of the "Drug Standards of the Ministry of Health of the People's Republic of China" Traditional Chinese Medicine Prescriptions: Scutellaria baicalensis 137g, menthol 2g and Yanreqing capsules Extract 161g, made into 1000 pieces; the Yanreqing ...

AI Technical Summary

Problems solved by technology

[0007] Above two kinds of methods all have following shortcoming: 1, menthol is directly added in the form of solid powder, is not easy to mix uniformly; Volatilization loss is easy in mixing process and coating heating process, causes the identification item of menthol in the finished product not to be. Qualified, traits unqualified and other issues

2. Moreover, menthol has a hydrophilic and hydrophobic structure, and it is directly added in the form of solid powder. During the granulation process, there is a problem that the powder and auxiliary materials are not easy to mix. When pressing, it is not easy to bond with other auxiliary materials, resulting in Uneven finished product content, unqualified tablet hardness, unqualified friability, loose tablets and other problems, uncontrollable quality, long working hours, and high costs