Emulsion type ointment
An emulsifying, ointment technology, applied in the directions of ointment delivery, emulsion delivery, oil/fat/wax inactive ingredients, etc., can solve the problems of difficulty in ensuring the safety of clinical use of preparations, and difficulty in determining the quality control standards of excipients, and achieves a high level of improvement. Penetration, low cost and strong product stability
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Image
Examples
Embodiment 1
[0016] Mixed system of soybean oil and water, sodium alginate powder, calcium salt solution (calcium phosphate, calcium chloride, calcium carbonate, etc. are all acceptable), distilled water, Tween system:
[0017] Add 30%wt emulsifier Tween of the finished ointment to the soybean oil and water mixed system, dissolve sodium alginate in the water phase of the oil-water mixed system, and the added amount shall not be less than 1%wt and not more than 5% by weight of the finished ointment. %wt, stirring at a speed of not less than 500 rpm for more than 30 minutes, and finally adding calcium salt solution dropwise in an amount of not less than 0.5% and not more than 8% of the weight of the finished ointment, that is, an ointment preparation is made. The consistency and viscosity (ηc) of the emulsified ointment are tested to be not less than 3.18mPa.s, and the water loss rate test shows that the water loss rate of the emulsified ointment for 5 hours is not higher than 6.73%wt. And t...
Embodiment 2
[0019] Sesame oil, water mixed system, sodium alginate powder, glutaraldehyde, Siban system:
[0020] In the sesame oil and water mixed system, add 1%wt of the emulsifier Span of the finished ointment, dissolve sodium alginate in the oil-water mixed system, and the added amount is not less than 0.5%wt and not more than 5%wt of the weight of the finished ointment solution, stirred at a speed of not less than 500 rev / s for more than 30 minutes, and finally added dropwise glutaraldehyde solution, and the amount of glutaraldehyde added dropwise accounted for not less than 0.5% and not more than 8% of the weight ratio of the finished ointment, that is, the prepared into ointment preparations. It is found through testing that the consistency and viscosity (ηc) of the emulsified ointment are not lower than 3.18mPa.s, and the water loss rate test shows that the water loss rate of the emulsified ointment is not higher than 6.73%wt within 5 hours. The emulsified ointment was co-culture...
Embodiment 3
[0022] Liquid paraffin, water mixed system, potassium alginate powder, chitosan, AOT system:
[0023]In the liquid paraffin and water mixed system, add 3%wt emulsifier AOT of the finished ointment, dissolve sodium alginate in the oil-water mixed system, and the proportion of the added amount to the weight of the finished ointment is not less than 0.5%wt and not more than 5%wt Solution, stirred at a speed of not less than 500 rev / s for more than 30 minutes, and finally added dropwise chitosan solution, the amount of chitosan added dropwise accounted for not less than 0.5% and not more than 10% by weight of the finished ointment, that is Made into an ointment preparation. It is found through testing that the consistency and viscosity (ηc) of the emulsified ointment are not lower than 3.18mPa.s, and the water loss rate test shows that the water loss rate of the emulsified ointment is not higher than 6.73%wt within 5 hours. The emulsified ointment was co-cultured with the cells, ...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More