Method for preparing mangiferin

A mangiferin and aqueous solution technology, applied in the direction of organic chemistry, can solve the problems of operator and environmental damage, many mangiferin impurities, complicated operation process and other problems, and achieve the effects of low production cost, less impurities and simple operation process
CN101973985AInactive Publication Date: 2011-02-16广西中医学院
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
广西中医学院
Publication Date
2011-02-16
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a method for preparing mangiferin. The method comprises the following steps of: taking a natural plant as a raw material; and performing the processes of solvent extraction, concentration, separation and purification. The method is characterized in that: the solvent is the aqueous solution of an alkali; and the processes comprise the following steps of: adding the natural plant into the aqueous solution of the alkali in an amount of 8 to 10 times based on the weight part of the natural plant; heating for boiling for 30 to 50 minutes; filtering extracting solution for later use; adding the aqueous solution of the alkali in the amount of 8 to 10 times based on the weight part of the natural plant again; boiling for 10 to 30 minutes; merging the extracting solution obtained from twice filtering; adding the aqueous solution of an acid into the merged solution for precipitating; filtering for removing impurities; and obtaining the mangiferin with the purity of over 95 percent by performing the processes such as enriching, decoloring and refining on the filtrate. The method has a simple process and is suitable for industrial production.
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Description

technical field

[0001] The invention relates to a method for extracting active ingredients from plants, in particular to a method for extracting mangiferin from natural plants. technical background

[0002] Mangiferin (mangiferin, I), also known as mangiferin and anemarrhena, is a carbon glycoside of tetrahydroxypyridine, which belongs to the biphenylpyrazone compound. Mangiferin can be extracted from the leaves, fruits, bark and lilies of mango trees and almond trees in the Anacardiaceae family, Anemarrhena chinensis, Northeast Gentiana, Swert sprouts, Hypericum sampsonii Hance, etc. Its molecular formula is C 19 h 18 o 11 The molecular weight is 422, and the structural formula is as follows:

[0003]

[0004] Modern pharmacology and clinical studies have proved that mangiferin has many physiological activities and pharmacological effects, such as anti-tumor effect, anti-lipid peroxidation, immune regulation, anti-diabetes, anti-inflammatory, pain relief, anti-virus,...

Claims

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