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Composite antioxidant for improving semen quality of male animal

A compound antioxidant and animal technology, applied in animal feed, animal feed, additional food elements, etc., can solve the problems of sperm motility, inaccurate effect, inconvenient application, etc.

Active Publication Date: 2011-03-02
SHANGHAI XINNONG FEED
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Some researchers believe that a single addition of dihydropyridine can increase the amount of ejaculation, but it has little effect on sperm motility, and the safety of long-term use of high-dose synthetics is worrying; inconvenient and ineffective

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The components of this example and their weight percentages are: 50% vitamin E 7.0%, 92% vitamin C 13.0%, 20% tea polyphenol 30.0%, and 95% lipoic acid 5.0 %, corncob meal (carrier) 45.0%, fully mixed to obtain the compound antioxidant, add 1.5g compound antioxidant per kg of feed 36 adult SPF-grade male SD rats are fed, and the rat serum after 22 days SOD enzyme activity increased by 11.8% (234.07U / ml: 198.36U / ml), NO free radicals in serum decreased by 12.08% (29.28: 33.30umol / ml), serum malondialdehyde (MDA) content decreased by 15.2% (6.63: 7.82nmol / ml), the sperm count of rat semen increased by 34.7% (30.64×10 5 / ml: 22.75×10 5 / ml), a grade sperm count increased by 27.0% (6.32×10 5 / ml: 4.98×10 5 / ml), sperm motility increased by 10.3% (89.06%: 80.75%).

Embodiment 2

[0021] Taking the components in this example and their weight percentages as follows: 50% vitamin E 8.0%, 92% vitamin C 15.0%, 20% tea polyphenol 20.04%, and 95% lipoic acid 4.0%, corncob powder (carrier) 53.0%, fully mixed to obtain the compound antioxidant, add 2.0g compound antioxidant per kg of feed to 20 70-day-old male mice, and feed the mouse serum after 21 days The SOD enzyme activity increased by 4.8% (226.96U / ml:216.57U / ml), the serum GSH-Px activity increased by 4.7% (2931.83U / ml:2800.22U / ml), and the serum NO content decreased by 25.07% (21.53μmol / L) :28.73μmol / L), serum malondialdehyde (MDA) content decreased by 18.1% (5.91nmol / L:7.22nmol / L), mouse serum testosterone concentration increased by 51.51% (834.14U / ml:550.53U / ml) , The sperm count of mouse semen increased by 15.2% (30.18×10 6 / ml: 26.2×10 6 / ml), a grade sperm count increased by 16.2% (8.59×10 6 / ml: 7.40×10 6 / ml), sperm motility increased by 7.5% (93.3%: 86.8%).

Embodiment 3

[0023] Taking the components of this example and their weight percentages are: 50% vitamin E 8.5%, 92% vitamin C 12.0%, 20% tea polyphenols 40.0%, and 95% lipoic acid 5.0%, corncob meal (carrier) 34.5%, fully mixed to get the compound antioxidant, add 2.0g compound antioxidant per kg of feed to 15 adult boars, feed the boar semen after 45 days Increased by 7.54% (216.7ml: 200.3ml), increased sperm count by 11.86% (176 million / ml: 158 million / ml), and sperm motility increased by 7.27% (78.21%: 72.91%).

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PUM

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Abstract

The invention relates to a composite antioxidant for improving reproductive capacity of a male animal, which belongs to the technical field of animal feed and comprises the following components by weight percent: 6.5-8.5% of food grade vitamin E, 11.0-15.5% of food grade vitamin C, 20.0-40.0% of food grade tea polyphenols, 4.0-6.0% of food grade thioctic acid and the balance of food grade corncobpowder which is taken as a carrier. The composite antioxidant can significantly reduce the content of nitrogen oxide free radicals and malonaldehyde in serum, improve the activity of SOD enzyme, significantly increase the number of sperms and the number of a grade sperms (the sperms with strong activity) in a male rat and improve the reproductive capacity of the male animal.

Description

Technical field [0001] The invention relates to a composite antioxidant in the technical field of animal feed, in particular to a composite antioxidant that improves the quality of male animal semen. Background technique [0002] A large number of studies have proved that due to bad environmental conditions such as high temperature and air, unreasonable food structure, excessive intake of synthetic compounds or drugs affect the reproductive health of male animals. [0003] Semen quality is the main factor that affects the reproductive ability of male animals, and sperm, especially the plasma membrane, is rich in unsaturated fatty acids. The presence of unsaturated fatty acids is conducive to maintaining the fluidity of the membrane. The fluidity of the membrane is due to sperm movement and acrosome Necessary for fertilization processes such as reaction and sperm-egg fusion. However, these polyunsaturated fatty acids are easily oxidized under aerobic conditions, which reduces the f...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/18A23K1/16A23K10/30A23K20/174A23K50/00
Inventor 徐建雄陈小连
Owner SHANGHAI XINNONG FEED
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