Method for preparing cinnamon oil microemulsion

A technology of cinnamon oil and oil microemulsion, which is applied in the directions of food preparation, application, food science, etc., can solve the problems that the application of emulsion formulation has not made great progress, phase inversion or crack oxidation, complicated preparation process, etc., and can achieve strong illumination. Good stability, improved bioavailability and simple process

Inactive Publication Date: 2011-03-02
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, ordinary emulsion is a thermodynamically unstable heterogeneous phase system, which is easy to stratify, flocculate, phase invert or rupture and oxidize, and is not easy to store, and the preparation process is complicated.
At present, the important dosage forms of cinnamon used in clinical practice include capsules, granules, plasters, etc., and great progress has not been made in the application of emulsion dosage forms.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Cinnamon oil 0.45g, RH-40 0.99g, Span 80 0.33g, isopropanol 0.44g, IPM 0.39g, deionized water 2.2g. Take 0.45 grams of cinnamon oil, 0.99 grams of RH-40, 0.33 grams of Span 80, 0.44 grams of isopropanol, and 0.39 grams of IPM in the same container, stir evenly under a magnetic stirrer, and add deionized drops drop by drop at 40°C Water was added dropwise while stirring, and 2.2 grams of deionized water was added to obtain cinnamon oil microemulsion.

Embodiment 2

[0016] Cinnamon oil 0.42g, RH-40 1.01g, Span 80 0.34g, isopropanol 0.45g, IPM 0.35g, deionized water 2.33g. Take 0.42 grams of cinnamon oil, 1.01 grams of RH-40, 0.34 grams of Span 80, 0.45 grams of isopropanol, and 0.35 grams of IPM in the same container, stir evenly under a magnetic stirrer, and add deionized drops drop by drop at 40°C Water was added dropwise while stirring, and 2.33 grams of deionized water was added to obtain cinnamon oil microemulsion.

Embodiment 3

[0018] Cinnamon oil 0.90g, Co-40 1.31g, RH-40 0.44g, absolute ethanol 1.75g, IPM 0.62g, deionized water 3.02g. Take 0.90 grams of cinnamon oil, 1.31 grams of Co-40, 0.44 grams of RH-40, 1.75 grams of absolute ethanol, and 0.62 grams of IPM in the same container, stir evenly under a magnetic stirrer, and add deionized water, while stirring while adding dropwise, add 3.02 grams of deionized water to obtain cinnamon oil microemulsion.

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PUM

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Abstract

The invention discloses a method for preparing cinnamon oil microemulsion, which is a cinnamon oil microemulsion system comprising the components of cinnamon oil, a composite emulsifier, an auxiliary emulsifier, deionized water and the like. Every 100 ml of the microemulsion contains 2 to 17 g of cinnamon oil, 20 to 35 g of composite emulsifier, 10 to 15 g of auxiliary emulsifier, 2 to 18 g of dispersing agent and the balance deionized water. The components are uniformly stirred by magnetic force at 20 to 60 DEG C to obtain the microemulsion which is packed and sterilized. The invention adopts a small amount of emulsifier, has simple process and ensures high oil carrying capacity of the prepared microemulsion and high bioavailability. The particle size of the microemulsion is between 25 and 40 nm, the oil carrying capacity is 2 to 17% and the entrapment efficiency is 80%.

Description

technical field [0001] The invention relates to a formula and a preparation process of cinnamon oil microemulsion, belonging to the technical field of health food preparation. Background technique [0002] Cinnamon oil is the volatile oil extracted by steam distillation from the dry branches and leaves of Cinnamomum Cassia Presl. All herbal medicines of past dynasties are listed as top grade, and it is believed that it has the effects of nourishing fire and supporting yang, drawing fire back to its source, dispelling cold and relieving pain, promoting blood circulation and stimulating menstruation. Traditional Chinese medicine is used as a medicine for treating impotence, cold palace, cold waist and knee pain, shortness of breath due to kidney deficiency, dizziness due to yang deficiency, red eyes and sore throat, cold pain in trusted subordinates, vomiting and diarrhea due to deficiency and cold, cold hernia, running dolphins, amenorrhea, and dysmenorrhea. Modern studies h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L33/00
Inventor 易醒肖小年李莉郭烨易海斌薄春燕
Owner NANCHANG UNIV
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