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Traditional Chinese medicine composition as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition and its preparation, can solve the problems of human toxic and side effects, unsatisfactory curative effect, etc., and achieve the effects of improved curative effect, remarkable curative effect and simple operation

Inactive Publication Date: 2012-05-02
SHANDONG ACAD OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many drugs for the treatment of myocardial ischemia, but the curative effect is not satisfactory, and long-term use will cause certain toxic and side effects to the human body

Method used

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  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof
  • Traditional Chinese medicine composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Epimedium extract 2g, kudzu root extract 2g, astragalus extract 2g, hawthorn leaf extract 1g, notoginseng extract 0.2g, cassia twig extract 0.5g.

[0029] The preparation method is:

[0030] 1. Preparation of each medicinal material extract

[0031] a. Preparation of Panax notoginseng extract: Mix Panax notoginseng with 6-10 mass times of 30-60% ethanol, heat and reflux at 70°C for two extractions, each extraction for 40 min, combine the two extracts, and recover the ethanol Spray-dried or concentrated into a thick paste with a relative density of 1.30-1.31 at 80°C, dried under reduced pressure at 60°C to obtain the Panax notoginseng extract;

[0032] b. Preparation of hawthorn leaf extract: Soak the hawthorn leaves with clean water and deionized water, remove the stems and roots after drying, soak the leaves with 20 times the mass of deionized water for 1 h, filter and freeze-dry the filtrate Hawthorn leaf extract;

[0033] c. Preparation of Astragalus extract: add ...

Embodiment 2

[0039] Epimedium extract 1g, kudzu root extract 3g, astragalus extract 5g, hawthorn leaf extract 1g, notoginseng extract 0.1g, cassia twig extract 0.4g.

[0040]The preparation method is the same as in Example 1.

Embodiment 3

[0042] Epimedium extract 5g, kudzu root extract 1g, astragalus extract 1g, hawthorn leaf extract 2g, notoginseng extract 0.3g, cassia twig extract 0.7g.

[0043] The preparation method is the same as in Example 1.

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Abstract

The invention discloses a traditional Chinese medicine composition, comprising the following effective medicament components in parts by weight: 1-5 parts of epimedium herb extract, 1-5 parts of kudzu root extract, 1-5 parts of radix astragali extract, 0.5-2 parts of hawthorn leaf extract, 0.1-0.3 part of radix pseudo-ginseng extract and 0.3-0.7 part of cassia twig extract. The invention also provides a preparation method and an application of the traditional Chinese medicine composition. The traditional Chinese medicine composition utilizes the epimedium herb extract, the kudzu root extract and the radix astragali extract as main components, and is additionally provided with the hawthorn leaf extract, the radix pseudo-ginseng extract and the cassia twig extract, and the effective components are mutually complemented to achieve the functions of mutual synergy and improved curative effect. The obtained traditional Chinese medicine composition has obvious curative effect and no obvious toxic or side effect. The preparation method in the invention is simple in operation, and the obtained composition has good curative effect which is obviously superior to that of the existing drug when being used for curing myocardial ischemia, and has practicability.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and application, in particular to a medicine for treating myocardial ischemia and its preparation method and application. Background technique [0002] Myocardial ischemia refers to a pathological state in which the blood perfusion of the heart is reduced, resulting in reduced oxygen supply to the heart, abnormal myocardial energy metabolism, and failure to support the normal work of the heart. Clinically, the main and most common cause of myocardial ischemia is coronary artery (occasionally pulmonary artery) stenosis. The main cause of coronary artery stenosis is atherosclerosis. Heart disease caused by coronary atherosclerosis is commonly known as coronary heart disease. Therefore, coronary heart disease is the "culprit" of myocardial ischemia. [0003] Myocardial ischemia may have many adverse effects on the heart and the whole body. Myocardial ischemi...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/734A61K9/20A61K9/48A61K9/16A61P9/10
Inventor 李贵海孙付军王维勋陆永辉闫雪生
Owner SHANDONG ACAD OF CHINESE MEDICINE